UFSP1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

UFM1 specific peptidase 1 (inactive) is a protein that in humans is encoded by the UFSP1 gene.[5]

AliasesUFSP1, UFSP, UFM1-specific peptidase 1 (inactive), UFM1 specific peptidase 1 (inactive)
End100,889,715 bp[1]
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UFSP1
Identifiers
AliasesUFSP1, UFSP, UFM1-specific peptidase 1 (inactive), UFM1 specific peptidase 1 (inactive)
External IDsOMIM: 611481; MGI: 1917490; HomoloGene: 80245; GeneCards: UFSP1; OMA:UFSP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001015072

NM_027356

RefSeq (protein)

NP_001015072

NP_081632

Location (UCSC)Chr 7: 100.89 – 100.89 MbChr 5: 137.29 – 137.29 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a protein that is similar to other Ufm1-specific proteases. Studies in mouse determined that Ufsp1 releases Ufm1 (ubiquitin-fold modifier 1) from its bound conjugated complexes which also makes it into an active form. Because the human UFSP1 protein is shorter on the N-terminus and lacks a conserved Cys active site, it is predicted to be non-functional.[provided by RefSeq, Nov 2009].[5]

References

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