USP25

USP25
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MUX
Identifiers
Aliases	USP25, USP21, ubiquitin specific peptidase 25
External IDs	OMIM: 604736; MGI: 1353655; HomoloGene: 8374; GeneCards: USP25; OMA:USP25 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	15,880,064 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	76,913,668 bp
RNA expression pattern
	Top expressed in
	sperm; ; Skeletal muscle tissue of rectus abdominis; ; glutes; ; amniotic fluid; ; muscle of thigh; ; biceps brachii; ; Achilles tendon; ; Skeletal muscle tissue of biceps brachii; ; gastrocnemius muscle; ; vastus lateralis muscle;
	Top expressed in
	muscle of thigh; ; knee joint; ; ciliary body; ; spermatid; ; blood; ; vastus lateralis muscle; ; granulocyte; ; fetal liver hematopoietic progenitor cell; ; genital tubercle; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	ATPase binding; peptidase activity; cysteine-type peptidase activity; ubiquitin binding; protein binding; hydrolase activity; ubiquitin protein ligase binding; thiol-dependent deubiquitinase; ubiquitin-like protein-specific protease activity; cysteine-type endopeptidase activity;
Cellular component	endoplasmic reticulum; nucleus; cytoplasm; cytosol;
Biological process	protein K63-linked deubiquitination; protein K48-linked deubiquitination; negative regulation of ERAD pathway; ubiquitin-dependent protein catabolic process; proteolysis; protein deubiquitination; regulation of protein stability;
	Sources:Amigo / QuickGO
Orthologs
	29761
	30940
	ENSG00000155313
	ENSMUSG00000022867
	Q9UHP3
	P57080
NM_001283041; NM_001283042; NM_013396; NM_001352560; NM_001352561;
	NM_001388299; NM_001388300; NM_001388301; NM_001388302
	NM_013918
	NP_001269970; NP_001269971; NP_037528; NP_001339489; NP_001339490
	NP_038946
	Wikidata
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