Uroplakin-3a

UPK3A
Identifiers
Aliases	UPK3A, UP3A, UPIII, UPIIIA, UPK3, uroplakin 3A
External IDs	OMIM: 611559; MGI: 98914; GeneCards: UPK3A
Gene location (Human)
Chr.	Chromosome 22 (human)
End	45,295,874 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	84,906,748 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; mucosa of urinary bladder; ; monocyte; ; prostate; ; muscle of thigh; ; granulocyte; ; muscle of arm; ; biceps brachii; ; skeletal muscle tissue; ; deltoid muscle;
	Top expressed in
	transitional epithelium of urinary bladder; ; Transitional epithelium of renal pelvis; ; transitional epithelium of ureter; ; medullary collecting duct; ; male urethra; ; epithelium of male urethra; ; right kidney; ; epithelium of female urethra; ; morula; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	extracellular exosome; endoplasmic reticulum membrane; apical plasma membrane; membrane; integral component of membrane; endoplasmic reticulum; apical plasma membrane urothelial plaque;
Biological process	kidney development; urea transport; epithelial cell differentiation; sodium ion homeostasis; potassium ion homeostasis; urinary bladder development; cell morphogenesis; water transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	7380
	22270
	ENSG00000100373
	ENSMUSG00000022435
	O75631
	Q9JKX8
	NM_001167574; NM_006953
	NM_023478
	NP_001161046; NP_008884
	NP_075967
	Wikidata
View/Edit Human	View/Edit Mouse

Uroplakin-3a (UP3a) is a protein that in humans is encoded by the UPK3A gene.^[5]^[6]

AliasesUPK3A, UP3A, UPIII, UPIIIA, UPK3, uroplakin 3A

End45,295,874 bp^[1]

Quick facts UPK3A, Identifiers ...

Close

The protein is found in the urinary bladder and contributes to the distensibility of this organ.^[7] It is also found in the renal pelvis, ureter, and prostatic urethra.

References