VARS

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Valyl-tRNA synthetase is an enzyme that in humans is encoded by the VARS gene.[5][6]

AliasesVARS1, VARS, NDMSCA, valyl-tRNA synthetase 1, G7A, VARS2, valyl-tRNA synthetase
End31,795,752 bp[1]
Quick facts VARS1, Identifiers ...
VARS1
Identifiers
AliasesVARS1, VARS, NDMSCA, valyl-tRNA synthetase 1, G7A, VARS2, valyl-tRNA synthetase
External IDsOMIM: 192150; MGI: 90675; HomoloGene: 4587; GeneCards: VARS1; OMA:VARS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006295

NM_011690

RefSeq (protein)

NP_006286
NP_006286.1

NP_035820

Location (UCSC)Chr 6: 31.78 – 31.8 MbChr 17: 35.22 – 35.24 Mb
PubMed search[3][4]
Wikidata
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Function

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.[6]

See also

References

Further reading

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