VU0155041

VU0155041
Identifiers
	IUPAC name (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid;
CAS Number	1263273-14-8;
PubChem CID	888023;
IUPHAR/BPS	3323;
ChemSpider	776108;
ChEMBL	ChEMBL578988;
Chemical and physical data
Formula	C14H15Cl2NO3
Molar mass	316.18 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC[C@H]([C@H](C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)C(=O)O;
	InChI InChI=1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20)/t11-,12+/m0/s1; Key:VSMUYYFJVFSVCA-NWDGAFQWSA-N;

VU0155041 is an experimental drug that is a positive allosteric modulator for the glutamate receptor mGluR4. In animal studies it has anti-Parkinsonian action, reduces neuropathic pain such as allodynia, and counteracts the effects of opioid addiction.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]^[9]

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Identifiers

IUPAC name (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid
CAS Number	1263273-14-8
PubChem CID	888023
IUPHAR/BPS	3323
ChemSpider	776108
ChEMBL	ChEMBL578988
Chemical and physical data
Formula	C₁₄H₁₅Cl₂NO₃
Molar mass	316.18 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CC[C@H]([C@H](C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)C(=O)O
InChI InChI=1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20)/t11-,12+/m0/s1 Key:VSMUYYFJVFSVCA-NWDGAFQWSA-N