Vibralactone
From Wikipedia, the free encyclopedia
Vibralactones are a group of related terpenoid chemical compounds, the first of which were isolated from the Basidiomycete Boreostereum vibrans in 2006.[1] Additional vibralactones have also been isolated from the fungus Stereum hirsutum.[2]
Vibralactone A has attracted research interest because it is an inhibitor of pancreatic lipase (IC50 0.4 μg/mL) with in vitro activity comparable to that of the obesity drug orlistat.[1][3]
Several laboratory syntheses of vibralactone A have been developed.[3][4]
Chemical structures
 Vibralactone A |  Vibralactone B |  Vibralactone C |
 Vibralactone D |  Vibralactone E |  Vibralactone F |