Virstatin

CAS Number

• 88909-96-0 ^Y

PubChem CID

• 145949

ChemSpider

• 128749

UNII

• 24SR2Q1Y6M

Virstatin

Identifiers
IUPAC name 4-(N-(1,8-naphthalimide))-n-butyric acid
CAS Number	88909-96-0 Y
PubChem CID	145949
ChemSpider	128749
UNII	24SR2Q1Y6M
ChEMBL	ChEMBL403272
CompTox Dashboard (EPA)	DTXSID10237406
Chemical and physical data
Formula	C16H13NO4
Molar mass	283.283 g·mol−1
3D model (JSmol)	Interactive image
Density	1.40 g/cm3
Melting point	180–183 °C (356–361 °F)
Boiling point	536.52 °C (997.74 °F)
SMILES c1cc2cccc3c2c(c1)C(=O)N(C3=O)CCCC(=O)O
InChI InChI=1S/C16H13NO4/c18-13(19)8-3-9-17-15(20)11-6-1-4-10-5-2-7-12(14(10)11)16(17)21/h1-2,4-7H,3,8-9H2,(H,18,19) Key:ZHXRDXTYPCPBTI-UHFFFAOYSA-N

Virstatin is a small molecule that inhibits the activity of the cholera protein, ToxT.^[1]

Its activity in cholera was first published in 2005 in a paper that described the screening of a chemical library in a phenotypic screen and subsequent testing of one of the hits in infected mice.^[1][2]

The compound is an isoquinoline alkaloid^[3] and can be synthesized by a simple two-step synthesis^[4]