WIPI1

WIPI1
Identifiers
Aliases	WIPI1, ATG18, ATG18A, WIPI49, WD repeat domain, phosphoinositide interacting 1
External IDs	OMIM: 609224; MGI: 1261864; HomoloGene: 117983; GeneCards: WIPI1; OMA:WIPI1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	68,457,513 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	109,502,793 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; sperm; ; gastrocnemius muscle; ; minor salivary glands; ; muscle of thigh; ; biceps brachii; ; left ventricle; ; skeletal muscle tissue; ; sural nerve; ; olfactory zone of nasal mucosa;
	Top expressed in
	seminal vesicula; ; interventricular septum; ; saccule; ; retinal pigment epithelium; ; muscle of thigh; ; right ventricle; ; stroma of bone marrow; ; submandibular gland; ; otic vesicle; ; granulocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphatidylinositol-3-phosphate binding; phosphatidylinositol-3,5-bisphosphate binding; androgen receptor binding; signaling receptor binding; estrogen receptor binding; protein binding; lipid binding;
Cellular component	cytoplasm; phagophore assembly site membrane; endosome; Golgi apparatus; membrane; Golgi membrane; trans-Golgi network; autophagosome membrane; endosome membrane; cytoskeleton; cytoplasmic vesicle; clathrin-coated vesicle; phagophore assembly site; cytosol; extrinsic component of membrane;
Biological process	vesicle targeting, trans-Golgi to endosome; autophagy; IRE1-mediated unfolded protein response; macroautophagy; autophagy of mitochondrion; protein lipidation; protein localization to phagophore assembly site; autophagy of nucleus; autophagosome assembly; cellular response to starvation;
	Sources:Amigo / QuickGO
Orthologs
	55062
	52639
	ENSG00000070540
	ENSMUSG00000041895
	Q5MNZ9
	Q8R3E3
	NM_017983; NM_001320772
	NM_145940
	NP_001307701; NP_060453
	NP_666052
	Wikidata
View/Edit Human	View/Edit Mouse

WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1), also known as Atg18 protein homolog (ATG18) and WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa), is a protein that in humans is encoded by the WIPI1 gene.^[5]^[6]^[7]