Madrigal was signed out of the Dominican Republic by the Anaheim Angels in 2001. After spending three years as an outfielder for the Cedar Rapids Kernels, the Angels' Low-A affiliate, Madrigal was converted to a pitcher in 2006.
At the end of the 2007 season, the Angels decided to protect Madrigal from the Rule 5 Draft by putting him on their 40-man roster on November 6. However, because Madrigal had spent 6 years in the minor leagues with one team, he became a free agent at the close of the 2007 World Series on October 29.
The Texas Rangers subsequently signed Madrigal to a contract on November 18, 2007.[1]
Madrigal made his debut for the Rangers on July 2, 2008, pitching in the 7th inning against the New York Yankees at old Yankee Stadium. Madrigal lasted only one-third of an inning, giving up six runs and Brett Gardner's first career hit.
Madrigal split the 2009 season between the major leagues and the Triple-A Oklahoma City RedHawks.
On April 8, 2010, Madrigal was placed on the 60-day disabled list. Upon his activation on June 24, Madrigal was outrighted off of the 40-man roster.[2] On November 6, Madrigal elected free agency.
On January 20, 2011, the New York Yankees signed Madrigal to a minor league contract with an invitation to spring training.[3] He was assigned to the Scranton/Wilkes-Barre Yankees to begin the season. On June 24, Madrigal was released by the Yankees organization.
On December 21, 2012, Madrigal signed a minor league contract with the Arizona Diamondbacks. In 22 games for the Triple-A Reno Aces, he compiled a 2.75 ERA with 41 strikeouts across 36 innings pitched. Madrigal was released by the Diamondbacks organization on June 11, 2013.[4]
Madrigal signed with the Chunichi Dragons for the 2013 season. On the year for the Dragons, Madrigal pitched to a 2-0 record with a 3.23 ERA and 28 strikeouts.
On January 23, 2014, Madrigal signed a minor league contract with the Washington Nationals organization. He was assigned to the Syracuse Chiefs to begin the season. On August 7, Madrigal was released.
Madrigal signed with the Uni-President 7-Eleven Lions of the Chinese Professional Baseball League prior to the 2015 season. In his tenure in the CPBL, Madrigal pitched to a 4-5 record with a 2.75 ERA and 48 strikeouts in 55+2⁄3 innings of work.[5]
On May 26, 2016, Madrigal signed with the Rieleros de Aguascalientes of the Mexican League. He was released by the Rieleros on June 24.[6]
On February 5, 2020, Madrigal signed with the Algodoneros de Unión Laguna of the Mexican League. Madrigal did not play in a game in 2020 due to the cancellation of the Mexican League season because of the COVID-19 pandemic.[7] On February 19, 2021, Madrigal was released.[8]
