Wilksby was mentioned in Domesday Book of 1086 as "Wilchesbi", with the Lord of the Manor being William I.[1] The name is derived from the Old Norse "Vilgeirr's/Vilgerth's" + "by", meaning the farmstead of Vilgeirr/Vilgerth.[2]
In 1931 the parish had a population of 30.[3] On 1 April 1936 the parish was abolished and merged with Wood Enderby.[4]
The church is dedicated to All Saints, though it may once have been St Mary, and is Grade II listed. Built of greenstone and red brick, It was renovated in 1895.
A church has known to have been on the site for at least 800 years, with the first recorded rector was Simon de Tynton in 1230. The stone font dates from the reign of King John (1166-1216), with the earliest written records from the church from 1563.