Zytron

Weed control herbicide From Wikipedia, the free encyclopedia

Zytron, also known as DMPA, is a chlorophenoxy herbicide.[1] It controls crabgrass and other weeds in turf preëmergently, and ants, chinch bugs and grubs.[2] It is used on baseball pitches in Australia.[3]

Quick facts Names, Identifiers ...
Zytron
Names
Preferred IUPAC name
N-[(2,4-Dichlorophenoxy)-methoxyphosphinothioyl]propan-2-amine
Other names
  • DMPA
  • O-2,4-Dichlorophenyl O-methyl isopropyl phosphoramidothioate
Identifiers
3D model (JSmol)
ChemSpider
DrugBank
UNII
  • InChI=1S/C10H14Cl2NO2PS/c1-7(2)13-16(17,14-3)15-10-5-4-8(11)6-9(10)12/h4-7H,1-3H3,(H,13,17)
    Key: PJFGPJQBWSEWKX-UHFFFAOYSA-N
  • CC(C)NP(=S)(OC)OC1=C(C=C(C=C1)Cl)Cl
Properties
C10H14Cl2NO2PS
Molar mass 314.16 g·mol−1
Appearance Solid[1]
Vapor pressure 6.14x10−5 mm Hg[1]
Hazards
Lethal dose or concentration (LD, LC):
  • 270 mg/kg (rat, oral)
  • >1000 mg/kg (dog, oral)
[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Zytron inhibits microtubule assembly, preventing mitosis. making it a Group 3 / D / K1, similar to dinitroanilines like trifluralin.[4] It was tested and commercially available in the US in 1959, and applied at 10-20 lbs per acre on turf,[5] a high rate compared to other herbicides.

Zytron disappears almost completely from the body within one hour of mammalian exposure.[2] It does not accumulate in soil and is non-harmful to microflora.[6] DMPA has in testing been applied at rates as high as 67 lbs per acre.[7]

Zytron may cause neurotoxicity in chickens. It is an organophosphorus ester, and other such chemicals are known to cause similar neurotoxicity. 100 mg/kg daily for 10 days was considered the minimum effective dose to observably alter hens' behaviour.[8]

Zytron has been sold under the tradenames "Dow Crabgrass Killer", "Dow 1329", "Dowco 118" and "T-H Crabgrass Killer."[9][10]

References

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