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α-N-Acetylglucosaminidase

Class of enzymes From Wikipedia, the free encyclopedia

The enzyme α-N-acetylglucosaminidase (EC 3.2.1.50, α-acetylglucosaminidase, N-acetyl-α-D-glucosaminidase, N-acetyl-α-glucosaminidase, α-D-2-acetamido-2-deoxyglucosidase) is a protein associated with Sanfilippo syndrome, with systematic name α-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase.[2][3][4][5] It catalyses the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-α-D-glucosaminides, and also UDP-N-acetylglucosamine.

Quick facts α--acetylglucosaminidase, Identifiers ...
α-N-acetylglucosaminidase
Human α-N-acetylglucosaminidase coloured by domain.[1] PDB: 4XWH​
Identifiers
SymbolNAGLU
NCBI gene4669
HGNC7632
OMIM609701
RefSeqNM_000263
UniProtP54802
Other data
EC number3.2.1.50
LocusChr. 17 q11-q21
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StructuresSwiss-model
DomainsInterPro
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