ADAM9

ADAM9
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	1M1V
Identificadores
Alias	ADAM9, CORD9, MCMP, MDC9, Mltng, ADAM metallopeptidase domain 9
IDs externos	OMIM: 602713 MGI: 105376 HomoloGene: 20824 GeneCards: ADAM9
Enfermedades genéticamente relacionadas
	distrofia de conos y bastones 9
Ontología génica
Función molecular	• collagen binding; • SH3 domain binding; • metal ion binding; • integrin binding; • GO:0070122 peptidase activity; • GO:0001948, GO:0016582 unión a proteína plasmática; • metalloendopeptidase activity; • laminin binding; • hydrolase activity; • metallopeptidase activity; • protein kinase C binding;
Componente celular	• componente integral de membrana; • membrana; • focal adhesion; • intrinsic component of external side of plasma membrane; • membrana plasmática; • región extracelular; • Exosoma (vesícula); • cell surface; • basolateral plasma membrane; • extracelular;
Proceso biológico	• positive regulation of membrane protein ectodomain proteolysis; • response to glucocorticoid; • positive regulation of macrophage fusion; • cell-cell adhesion mediated by integrin; • keratinocyte differentiation; • proteólisis; • monocyte activation; • response to calcium ion; • response to tumor necrosis factor; • positive regulation of keratinocyte migration; • adherencia celular; • response to manganese ion; • membrane protein ectodomain proteolysis; • positive regulation of protein secretion; • integrin-mediated signaling pathway; • positive regulation of cell adhesion mediated by integrin; • cell-matrix adhesion; • cellular response to lipopolysaccharide; • transforming growth factor beta receptor signaling pathway; • response to hydrogen peroxide; • migración celular; • cell adhesion mediated by integrin; • response to laminar fluid shear stress; • response to antineoplastic agent;
	Fuentes: Amigo / QuickGO
Ortólogos
	8754
	11502
	ENSG00000168615; ENSG00000282230
	ENSMUSG00000031555
	Q13443
	Q61072
	NM_001005845; NM_003816
	NM_001270996; NM_007404
	NP_003807
	NP_001257925; NP_031430
	Wikidata
Ver/Editar Humano	Ver/Editar Ratón

PDBBúsqueda ortóloga: PDBe RCSB

AliasADAM9, CORD9, MCMP, MDC9, Mltng, ADAM metallopeptidase domain 9

IDs externosOMIM: 602713 MGI: 105376 HomoloGene: 20824 GeneCards: ADAM9

Función molecular

• collagen binding
• SH3 domain binding
• metal ion binding
• integrin binding
• GO:0070122 peptidase activity
• GO:0001948, GO:0016582 unión a proteína plasmática
• metalloendopeptidase activity
• laminin binding
• hydrolase activity
• metallopeptidase activity
• protein kinase C binding

La proteína 9 que contiene el dominio de desintegrina y metaloproteinasa es una enzima que en humanos está codificada por el gen ADAM9.^[4]^[5]^[6]

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ADAM9

Interacciones

Referencias

Enlaces externos

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