DDR1

DDR1
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	3ZOS, 4AG4, 4BKJ, 4CKR, 5BVK, 5BVN, 5BVO, 5BVW, 5FDP
Identificadores
Alias	DDR1, CAK, CD167, DDR, EHGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE, discoidin domain receptor tyrosine kinase 1
IDs externos	OMIM: 600408 MGI: 99216 HomoloGene: 68212 GeneCards: DDR1
Ontología génica
Función molecular	• transferase activity; • nucleotide binding; • protein kinase activity; • collagen binding; • metal ion binding; • kinase activity; • GO:0001948, GO:0016582 unión a proteína plasmática; • transmembrane receptor protein tyrosine kinase activity; • protein tyrosine kinase collagen receptor activity; • protein tyrosine kinase activity; • ATP binding; • Receptor tirosina quinasa;
Componente celular	• componente integral de membrana; • membrana; • receptor complex; • membrana plasmática; • integral component of plasma membrane; • región extracelular; • Exosoma (vesícula); • extracelular;
Proceso biológico	• collagen-activated tyrosine kinase receptor signaling pathway; • branching involved in mammary gland duct morphogenesis; • fosforilación; • transmembrane receptor protein tyrosine kinase signaling pathway; • female pregnancy; • extracellular matrix organization; • ear development; • mammary gland alveolus development; • regulation of extracellular matrix disassembly; • smooth muscle cell migration; • smooth muscle cell-matrix adhesion; • regulation of cell-matrix adhesion; • fosforilación de proteína; • adherencia celular; • regulation of cell growth; • peptidyl-tyrosine phosphorylation; • lactancia; • wound healing, spreading of cells; • embryo implantation; • negative regulation of cell population proliferation; • peptidyl-tyrosine autophosphorylation; • protein autophosphorylation; • axon development; • neuron projection extension; • cell-matrix adhesion; • positive regulation of cell population proliferation; • diferenciación celular; • regulation of extracellular matrix organization;
	Fuentes: Amigo / QuickGO
Patrón de la expressión del ARN
	; ; ; ;
	Más referencias a datos de expressión
Ortólogos
	780
	12305
ENSG00000215522; ENSG00000137332; ENSG00000229767; ENSG00000230456; ENSG00000234078;
	ENSG00000204580; ENSG00000223680
	ENSMUSG00000003534
	Q08345
	Q03146
NM_001202521; NM_001202522; NM_001202523; NM_001297652; NM_001297653;
	NM_001297654; NM_001954; NM_013993; NM_013994
	NM_001198831; NM_001198833; NM_007584; NM_172962
NP_001189450; NP_001189451; NP_001189452; NP_001284581; NP_001284582;
	NP_001284583; NP_001945; NP_054699; NP_054700; NP_001284583.1; NP_054699.2
	NP_001185760; NP_001185762; NP_031610; NP_766550
	Wikidata
Ver/Editar Humano	Ver/Editar Ratón

PDBBúsqueda ortóloga: PDBe RCSB

AliasDDR1, CAK, CD167, DDR, EHGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE, discoidin domain receptor tyrosine kinase 1

IDs externosOMIM: 600408 MGI: 99216 HomoloGene: 68212 GeneCards: DDR1

Función molecular

• transferase activity
• nucleotide binding
• protein kinase activity
• collagen binding
• metal ion binding
• kinase activity
• GO:0001948, GO:0016582 unión a proteína plasmática
• transmembrane receptor protein tyrosine kinase activity
• protein tyrosine kinase collagen receptor activity
• protein tyrosine kinase activity
• ATP binding
• Receptor tirosina quinasa

La familia de receptores del dominio de discoidina, miembro 1, también conocida como DDR1 o CD167a (grupo de diferenciación 167a), es un gen humano.^[3]

[1]

[2]

[3]

DDR1

Referencias

Enlaces externos

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