DNM1

DNM1
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	1DYN, 2DYN, 2X2E, 2X2F, 3SNH, 3ZYC, 3ZYS, 4UUD, 4UUK, 5D3Q
Identificadores
Alias	DNM1, Dynamin-1, DNM, EIEE31, dynamin 1, DEE31
IDs externos	OMIM: 602377 MGI: 107384 HomoloGene: 123905 GeneCards: DNM1
Enfermedades genéticamente relacionadas
	trastorno por déficit de atención con hiperactividad, infancy electroclinical syndrome
Ontología génica
Función molecular	• nucleotide binding; • protein dimerization activity; • GTP binding; • GO:0001948, GO:0016582 unión a proteína plasmática; • hydrolase activity; • protein kinase binding; • microtubule binding; • unión a ARN (RNA); • GO:0006184 GTPase activity; • protein C-terminus binding; • D2 dopamine receptor binding; • GO:0032403 protein-containing complex binding; • nitric-oxide synthase binding; • identical protein binding; • SH3 domain binding;
Componente celular	• citoplasma; • photoreceptor inner segment; • vaina de mielina; • sinapsis; • membrane coat; • microtúbulo; • citoesqueleto; • Exosoma (vesícula); • mitochondrial membranes; • aparato de Golgi; • membrana plasmática; • Vesícula sináptica; • varicosity; • núcleo celular; • Nucleoplasma; • GO:0097483, GO:0097481 postsynaptic density; • membrana; • axón; • GO:0016023 cytoplasmic vesicle; • GO:0009327 complejo macromolecular; • Espina dendrítica; • dendritic spine head; • postsynaptic membrane; • photoreceptor ribbon synapse; • presynaptic endocytic zone membrane; • postsynaptic endocytic zone membrane; • glutamatergic synapse;
Proceso biológico	• endocitosis; • ephrin receptor signaling pathway; • adult locomotory behavior; • synaptic transmission, GABAergic; • toxin transport; • audición; • protein tetramerization; • endosome organization; • clathrin-dependent endocytosis; • fisión mitocondrial; • dynamin family protein polymerization involved in mitochondrial fission; • membrane fusion; • synaptic vesicle budding from presynaptic endocytic zone membrane; • G protein-coupled receptor internalization; • receptor-mediated endocytosis; • receptor internalization; • positive regulation of synaptic vesicle recycling; • synaptic vesicle endocytosis; • regulation of synapse structure or activity; • modulation of chemical synaptic transmission; • postsynaptic neurotransmitter receptor internalization; • regulation of synaptic vesicle endocytosis; • positive regulation of synaptic vesicle endocytosis; • response to amyloid-beta;
	Fuentes: Amigo / QuickGO
Patrón de la expressión del ARN
	Más referencias a datos de expressión
Ortólogos
	1759
	13429
	ENSG00000106976
	ENSMUSG00000026825
	Q05193
	P39053
NM_001005336; NM_001288737; NM_001288738; NM_001288739; NM_004408;
	NM_001374269
	NM_001301737; NM_010065; NM_001368679
NP_001005336; NP_001275666; NP_001275667; NP_001275668; NP_004399;
	NP_001361198
	NP_001288666; NP_034195; NP_001355608
	Wikidata
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