KCNE2

KCNE2
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	2M0Q
Identificadores
Alias	KCNE2, ATFB4, LQT5, LQT6, MIRP1, potassium voltage-gated channel subfamily E regulatory subunit 2
IDs externos	OMIM: 603796 MGI: 1891123 HomoloGene: 71688 GeneCards: KCNE2
Enfermedades genéticamente relacionadas
	Síndrome de Romano-Ward
Ontología génica
Función molecular	• potassium channel activity; • protein homodimerization activity; • transmembrane transporter binding; • delayed rectifier potassium channel activity; • voltage-gated ion channel activity; • potassium channel regulator activity; • GO:0001948, GO:0016582 unión a proteína plasmática; • voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization; • voltage-gated potassium channel activity; • inward rectifier potassium channel activity;
Componente celular	• componente integral de membrana; • membrana; • voltage-gated potassium channel complex; • membrana plasmática; • lisosoma; • retículo endoplasmático; • aparato de Golgi; • cell surface;
Proceso biológico	• negative regulation of voltage-gated potassium channel activity; • tongue development; • regulation of inward rectifier potassium channel activity; • positive regulation of voltage-gated calcium channel activity; • regulation of ion transmembrane transport; • ventricular cardiac muscle cell action potential; • GO:0010260 envejecimiento; • cardiac muscle cell action potential involved in contraction; • ion transport; • potassium ion transport; • membrane repolarization; • membrane repolarization during action potential; • regulation of delayed rectifier potassium channel activity; • cardiac conduction; • potassium ion transmembrane transport; • regulation of membrane repolarization; • positive regulation of proteasomal protein catabolic process; • regulation of heart rate by cardiac conduction; • regulation of potassium ion transmembrane transport; • regulation of cyclic nucleotide-gated ion channel activity; • negative regulation of delayed rectifier potassium channel activity; • regulation of ventricular cardiac muscle cell membrane repolarization; • membrane repolarization during ventricular cardiac muscle cell action potential; • GO:0015915 transporte; • potassium ion export across plasma membrane; • potassium ion import across plasma membrane;
	Fuentes: Amigo / QuickGO
Ortólogos
	9992
	246133
	ENSG00000159197
	ENSMUSG00000039672
	Q9Y6J6
	Q9D808
	NM_172201; NM_005136
	NM_134110; NM_001358372
	NP_751951
	NP_598871; NP_001345301
	Wikidata
Ver/Editar Humano	Ver/Editar Ratón

PDBBúsqueda ortóloga: PDBe RCSB

AliasKCNE2, ATFB4, LQT5, LQT6, MIRP1, potassium voltage-gated channel subfamily E regulatory subunit 2

IDs externosOMIM: 603796 MGI: 1891123 HomoloGene: 71688 GeneCards: KCNE2

Función molecular

• potassium channel activity
• protein homodimerization activity
• transmembrane transporter binding
• delayed rectifier potassium channel activity
• voltage-gated ion channel activity
• potassium channel regulator activity
• GO:0001948, GO:0016582 unión a proteína plasmática
• voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
• voltage-gated potassium channel activity
• inward rectifier potassium channel activity

La subunidad reguladora 2 de la subfamilia E del canal dependiente de voltaje de potasio (KCNE2) es un gen humano que codifica para un canal de potasio activado por voltaje perteneciente a la familia relacionada con Isk. El gen está relacionado con el síndrome del QT largo.^[4]

Pertenece al grupos de subunidades reguladoras del canal dependiente de voltaje de potasio.^[5]

[1]

[2]

[3]

[4]

[5]

KCNE2

Referencias

Enlaces externos

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