PPARGC1B

PPARGC1B
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	3SP6
Identificadores
Alias	PPARGC1B, ERRL1, PERC, PGC-1(beta), PGC1B, PPARG coactivator 1 beta
IDs externos	OMIM: 608886 MGI: 2444934 HomoloGene: 15776 GeneCards: PPARGC1B
Enfermedades genéticamente relacionadas
	obesidad
Ontología génica
Función molecular	• GO:0001104 transcription coregulator activity; • AF-2 domain binding; • nuclear receptor coactivator activity; • unión a ARN (RNA); • unión de ácido nucleico; • transcription factor binding; • estrogen receptor binding;
Componente celular	• mediador; • mitocondria; • núcleo celular; • Nucleoplasma;
Proceso biológico	• mitochondrial transcription; • GO:0009373 regulation of transcription, DNA-templated; • osificación; • actin filament organization; • positive regulation of osteoclast differentiation; • positive regulation of DNA-binding transcription factor activity; • response to glucocorticoid; • bone trabecula formation; • positive regulation of bone resorption; • transcription, DNA-templated; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • GO:0072353 cellular response to reactive oxygen species; • positive regulation of alkaline phosphatase activity; • response to cAMP; • positive regulation of phosphorylation; • GO:0045996 negative regulation of transcription, DNA-templated; • intracellular estrogen receptor signaling pathway; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • positive regulation of cold-induced thermogenesis; • regulation of nucleic acid-templated transcription;
	Fuentes: Amigo / QuickGO
Ortólogos
	133522
	170826
	ENSG00000155846
	ENSMUSG00000033871
	Q86YN6
	Q8VHJ7
	NM_001172698; NM_001172699; NM_133263
	NM_133249; NM_001364996
	NP_001166169; NP_001166170; NP_573570
	NP_573512; NP_001351925
	Wikidata
Ver/Editar Humano	Ver/Editar Ratón

El coactivador del receptor gamma 1-beta activado por el proliferador de peroxisomas es una proteína que en humanos está codificada por el gen PPARGC1B.^[4]^[5]^[6]

PDBBúsqueda ortóloga: PDBe RCSB

AliasPPARGC1B, ERRL1, PERC, PGC-1(beta), PGC1B, PPARG coactivator 1 beta

IDs externosOMIM: 608886 MGI: 2444934 HomoloGene: 15776 GeneCards: PPARGC1B

Función molecular

• GO:0001104 transcription coregulator activity
• AF-2 domain binding
• nuclear receptor coactivator activity
• unión a ARN (RNA)
• unión de ácido nucleico
• transcription factor binding
• estrogen receptor binding

Datos rápidos Estructuras disponibles, PDB ...

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[4]

[5]

[6]

[1]

[2]

[3]

PPARGC1B

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