GLI1

GLI1
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	2GLI, 4BLB, 4KMD
Identifiants
Alias	GLI1
IDs externes	OMIM: 165220 MGI: 95727 HomoloGene: 3859 GeneCards: GLI1
Position du gène (humain)
Chr.	Chromosome 12 humain
Fin	57,472,268 bp
Position du gène (souris)
Chr.	Chromosome 10 (souris)
Fin	127,177,843 bp
Expression génique
	Fortement exprimé dans
	nerf tibial; ; nerf sural; ; muqueuse gastrique; ; endocol; ; testicule; ; dorsal motor nucleus of vagus nerve; ; rectum; ; sang; ; gonade; ; stromal cell of endometrium;
	Fortement exprimé dans
	spermatogonie; ; dent; ; molaire; ; crête génitale; ; lèvre; ; tubercule génital; ; derme; ; palais; ; epithelium of seminiferous tubule of testis; ; lower jaw;
	Plus de données d'expression de référence
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison ADN; sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; microtubule binding; liaison de chromatine; liaison ion métal; RNA polymerase II cis-regulatory region sequence-specific DNA binding; liaison protéique; Fixation d'acide nucléique; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Composant cellulaire	cytoplasme; cytosol; cil cellulaire; nucléoplasme; ciliary base; ciliary tip; axonème; noyau;
Processus biologique	epidermal cell differentiation; proximal/distal pattern formation; différenciation cellulaire; pituitary gland development; regulation of transcription, DNA-templated; positive regulation of smoothened signaling pathway; développement des poumons; positive regulation of cell migration; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; notochord regression; transcription, DNA-templated; régulation positive de la transcription dépendante de l'ADN; positive regulation of DNA replication; ventral midline development; développent d'un organisme multicellulaire; regulation of smoothened signaling pathway; régénération du foie; response to wounding; regulation of osteoblast differentiation; osteoblast differentiation; spermatogenèse; positive regulation of cell population proliferation; cerebellar cortex morphogenesis; regulation of hepatocyte proliferation; canonical Wnt signaling pathway; hedgehog; dorsal/ventral pattern formation; negative regulation of canonical Wnt signaling pathway; positive regulation of transcription by RNA polymerase II; digestive tract morphogenesis; prostate gland development; positive regulation of cardiac muscle cell proliferation; positive regulation of cell cycle G1/S phase transition;
	Sources:Amigo / QuickGO
Orthologues
	2735
	14632
	ENSG00000111087
	ENSMUSG00000025407
	P08151
	P47806
	NM_001160045; NM_001167609; NM_005269
	NM_010296
	NP_001153517; NP_001161081; NP_005260
	NP_034426
	Wikidata
Voir/Editer Humain	Voir/Editer Souris