IQGAP1

IQGAP1
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	1X0H, 2RR8, 3FAY, 3I6X
Identifiants
Alias	IQGAP1
IDs externes	OMIM: 603379 MGI: 1352757 HomoloGene: 74514 GeneCards: IQGAP1
Position du gène (humain)
Chr.	Chromosome 15 humain
Fin	90,502,239 bp
Position du gène (souris)
Chr.	Chromosome 7 (souris)
Fin	80,475,722 bp
Expression génique
	Fortement exprimé dans
	tendon calcanéen; ; epithelium of colon; ; monocyte; ; skin of hip; ; skin of thigh; ; artère coronaire droite; ; body of uterus; ; secondary oocyte; ; Descending thoracic aorta; ; lobe inférieur du poumon;
	Fortement exprimé dans
	left lung lobe; ; lobe pulmonaire droit; ; left colon; ; strie vasculaire; ; tibiofemoral joint; ; vestibular membrane of cochlear duct; ; corneal stroma; ; granulocyte; ; conjunctival fornix; ; corpuscule carotidien;
	Plus de données d'expression de référence
	; ; ; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	calcium liaison ionique; S100 protein binding; protein domain specific binding; liaison de complexe macromoléculaire; protein serine/threonine kinase activator activity; GTPase inhibitor activity; liaison protéique; protein phosphatase binding; protein kinase binding; phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity; mitogen-activated protein kinase binding; cadherin binding; fixation de la calmoduline; small GTPase binding; molecular adaptor activity;
Composant cellulaire	cytoplasme; cytosol; lateral plasma membrane; jonction cellule-cellule; membrane; microtubule cytoskeleton; cône de croissance; ruffle; extrinsic component of cytoplasmic side of plasma membrane; membrane plasmique; slit diaphragm; axone; midbody; cell leading edge; filament d'actine; actin cytosquelette; neuron projection; cytoplasmic ribonucleoprotein granule; microtubule; exosome; radeau lipidique; noyau; focal adhesion; secretory granule membrane; complexe macromoléculaire; ribonucléoprotéine;
Processus biologique	cellular response to calcium ion; glomerular visceral epithelial cell development; epidermal growth factor receptor signaling pathway; negative regulation of dephosphorylation; regulation of GTPase activity; cellular response to platelet-derived growth factor stimulus; cellular response to fibroblast growth factor stimulus; neuron projection extension; cellular response to epidermal growth factor stimulus; regulation of cytokine production; fibroblast growth factor receptor signaling pathway; platelet-derived growth factor receptor signaling pathway; transduction de signal; positive regulation of protein kinase activity; positive regulation of focal adhesion assembly; positive regulation of peptidyl-tyrosine autophosphorylation; positive regulation of GTPase activity; positive regulation of protein localization; positive regulation of dendrite development; positive regulation of MAP kinase activity; positive regulation of vascular associated smooth muscle cell migration; negative regulation of GTPase activity; response to angiotensin; neutrophil degranulation; regulation of mitotic cell cycle; migration cellulaire; viral process;
	Sources:Amigo / QuickGO
Orthologues
	8826
	29875
	ENSG00000140575
	ENSMUSG00000030536
	P46940
	Q9JKF1
	NM_003870
	NM_016721
	NP_003861
	NP_057930
	Wikidata
Voir/Editer Humain	Voir/Editer Souris

PDBRecherche d'orthologue : PDBe RCSB

AliasIQGAP1

IDs externesOMIM: 603379 MGI: 1352757 HomoloGene: 74514 GeneCards: IQGAP1

Chr.Chromosome 15 humain^[1]

IQGAP1 est une protéine d'échafaudage (participant à la transduction de signaux entre cellules en régulant l’activation des cascades moléculaires impliqués dans la transmission du signal) dont le gène est IQGAP1 situé sur le chromosome 15 humain.

[1]

[2]

[3]

[4]

IQGAP1

Notes et références

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