NOD1

NOD1
	Structure de la protéine NOD1. Basé sur l'identifiant PDB 2b1w.
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	2B1W, 2DBD, 2NSN, 2NZ7, 4E9M, 4JQW
Identifiants
Alias	NOD1
IDs externes	OMIM: 605980 MGI: 1341839 HomoloGene: 4440 GeneCards: NOD1
Position du gène (humain)
Chr.	Chromosome 7 humain
Fin	30,478,784 bp
Position du gène (souris)
Chr.	Chromosome 6 (souris)
Fin	54,949,597 bp
Expression génique
	Fortement exprimé dans
	nerf sural; ; left ovary; ; right lobe of thyroid gland; ; right ovary; ; gingival epithelium; ; upper lobe of left lung; ; left lobe of thyroid gland; ; apex of heart; ; subcutaneous adipose tissue; ; rate;
	Fortement exprimé dans
	ganglion mésentérique; ; granulocyte; ; subcutaneous adipose tissue; ; nerf ischiatique; ; poumon droit; ; rate; ; col de l'utérus; ; myocardium of ventricle; ; îlot de Langerhans; ; stroma of bone marrow;
	Plus de données d'expression de référence
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison nucléotide; protein homodimerization activity; liaison protéique; peptidoglycan binding; identical protein binding; cysteine-type endopeptidase activator activity involved in apoptotic process; CARD domain binding; liaison ATP; liaison de complexe macromoléculaire;
Composant cellulaire	cytoplasme; cytosol; membrane; membrane plasmique; basolateral plasma membrane; apical plasma membrane;
Processus biologique	regulation of apoptotic process; réponse de défense; detection of biotic stimulus; intracellular signal transduction; positive regulation of cell death; processus du système immunitaire; positive regulation of JNK cascade; positive regulation of xenophagy; positive regulation of NIK/NF-kappaB signaling; cellular response to muramyl dipeptide; JNK cascade; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of dendritic cell antigen processing and presentation; positive regulation of nitric-oxide synthase activity; defense response to bacterium; positive regulation of NF-kappaB transcription factor activity; protein complex oligomerization; detection of bacterium; positive regulation of interleukin-1 beta production; positive regulation of ERK1 and ERK2 cascade; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; positive regulation of I-kappaB kinase/NF-kappaB signaling; réponse inflammatoire; activation of cysteine-type endopeptidase activity involved in apoptotic process; nucleotide-binding oligomerization domain containing signaling pathway; transduction de signal; positive regulation of stress-activated MAPK cascade; defense response to Gram-positive bacterium; apoptose; système immunitaire inné; interleukin-1-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologues
	10392
	107607
	ENSG00000106100
	ENSMUSG00000038058
	Q9Y239
	Q8BHB0
	NM_006092; NM_001354849
	NM_001171007; NM_172729
	NP_006083; NP_001341778
	NP_001164478; NP_766317
	Wikidata
Voir/Editer Humain	Voir/Editer Souris

Le NOD1 (pour « Nucleotide-binding oligomerization domain-containing protein 1 ») est une protéine récepteur de type NOD. Son gène est le NOD1, situé sur le chromosome 7 humain.

PDBRecherche d'orthologue : PDBe RCSB

AliasNOD1

IDs externesOMIM: 605980 MGI: 1341839 HomoloGene: 4440 GeneCards: NOD1

Chr.Chromosome 7 humain^[1]

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