S6K1

RPS6KB1
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	3A60, 3A61, 3A62, 3WE4, 3WF5, 3WF6, 3WF7, 3WF8, 3WF9, 4L3J, 4L3L, 4L42, 4L43, 4L44, 4L45, 4L46, 4RLO, 4RLP
Identifiants
Alias	RPS6KB1
IDs externes	OMIM: 608938 MGI: 1270849 HomoloGene: 81703 GeneCards: RPS6KB1
Position du gène (humain)
Chr.	Chromosome 17 humain
Fin	59,950,574 bp
Position du gène (souris)
Chr.	Chromosome 11 (souris)
Fin	86,544,805 bp
Expression génique
	Fortement exprimé dans
	cellule endothéliale; ; Brodmann area 23; ; tendon calcanéen; ; gyrus temporal moyen; ; tibia; ; epithelium of colon; ; gingival epithelium; ; muscle biceps brachial; ; Skeletal muscle tissue of biceps brachii; ; Skeletal muscle tissue of rectus abdominis;
	Fortement exprimé dans
	glande lacrymale; ; tail of embryo; ; cellule de Paneth; ; tubercule génital; ; corpuscule rénal; ; uretère; ; condyle; ; fosse; ; substantia nigra; ; migratory enteric neural crest cell;
	Plus de données d'expression de référence
	; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	activité de transférase; protein kinase activity; liaison nucléotide; peptide binding; liaison protéique; identical protein binding; protein serine/threonine/tyrosine kinase activity; liaison ATP; activité kinase; protein serine/threonine kinase activity; ribosomal protein S6 kinase activity; PDZ domain binding; protein phosphatase 2A binding;
Composant cellulaire	cytoplasme; cytosol; membrane; synapse; nucléoplasme; surface cellulaire; membrane mitochondrial externe; jonction cellulaire; mitochondrie; perinuclear region of cytoplasm; neuron projection; noyau;
Processus biologique	germ cell development; response to amino acid; response to glucagon; response to organic cyclic compound; protein kinase B signaling; response to nutrient; phosphorylation; regulation of glucose import; response to testosterone; negative regulation of extrinsic apoptotic signaling pathway; cellular response to growth factor stimulus; skeletal muscle contraction; response to mechanical stimulus; vieillissement; response to leucine; cellular response to organic cyclic compound; positive regulation of mitotic cell cycle; negative regulation of apoptotic process; response to heat; response to glucocorticoid; response to glucose; response to peptide hormone; behavioral fear response; positive regulation of translation; response to organic substance; positive regulation of smooth muscle cell migration; response to tumor necrosis factor; response to insulin; response to lipopolysaccharide; negative regulation of insulin receptor signaling pathway; cellular response to hormone stimulus; mémoire à long terme; response to wounding; response to organonitrogen compound; response to electrical stimulus involved in regulation of muscle adaptation; skeletal muscle atrophy; cycle cellulaire; response to ethanol; positive regulation of translational initiation; migration cellulaire; réponse à une substance toxique; positive regulation of skeletal muscle tissue growth; regulation of translation; phosphatidylinositol-mediated signaling; transduction de signal; positive regulation of smooth muscle cell proliferation; apoptose; phosphorylation des protéines; cellular response to dexamethasone stimulus; cellular response to insulin stimulus; G1/S transition of mitotic cell cycle; peptidyl-serine phosphorylation; TOR signaling; cellular response to interferon-gamma; long-chain fatty acid import into cell; intracellular signal transduction; response to nutrient levels;
	Sources:Amigo / QuickGO
Orthologues
	6198
	72508
	ENSG00000108443
	ENSMUSG00000020516
	P23443
	Q8BSK8
	NM_001272042; NM_001272043; NM_001272044; NM_001272060; NM_003161
	NM_001114334; NM_028259; NM_001363162
NP_001258971; NP_001258972; NP_001258973; NP_001258989; NP_003152;
	NP_001356598; NP_001356599; NP_001356600; NP_001356601; NP_001356602; NP_001356603; NP_001356604; NP_001356605; NP_001356606; NP_001356607; NP_001356608
	NP_001107806; NP_082535; NP_001350091
	Wikidata
Voir/Editer Humain	Voir/Editer Souris