SCARB1

SCARB1
Identifiants
Alias	SCARB1
IDs externes	OMIM: 601040 MGI: 893578 HomoloGene: 21132 GeneCards: SCARB1
Position du gène (humain)
Chr.	Chromosome 12 humain
Fin	124,882,668 bp
Position du gène (souris)
Chr.	Chromosome 5 (souris)
Fin	125,418,158 bp
Expression génique
	Fortement exprimé dans
	right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; right lobe of liver; ; left ovary; ; right ovary; ; putamen; ; noyau caudé; ; subcutaneous adipose tissue; ; placenta;
	Fortement exprimé dans
	glande surrénale; ; cumulus cell; ; épithélium pigmentaire rétinien; ; crête génitale; ; artère carotide externe; ; artère carotide interne; ; neural layer of retina; ; lactiferous gland; ; Vésicule vitelline; ; corps ciliaire;
	Plus de données d'expression de référence
	; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	apolipoprotein binding; protein homodimerization activity; virus receptor activity; transporter activity; high-density lipoprotein particle receptor activity; phosphatidylserine binding; apolipoprotein A-I binding; lipopolysaccharide binding; low-density lipoprotein particle binding; 1-phosphatidylinositol binding; liaison protéique; high-density lipoprotein particle binding; lipopolysaccharide immune receptor activity; amyloid-beta binding; scavenger receptor activity;
Composant cellulaire	cytoplasme; integral component of membrane; endocytic vesicle membrane; intracellular membrane-bounded organelle; membrane; membrane plasmique; integral component of plasma membrane; surface cellulaire; lysosomal membrane; cavéole; exosome; microvillus membrane;
Processus biologique	cholesterol import; positive regulation of triglyceride biosynthetic process; regulation of phosphatidylcholine catabolic process; recognition of apoptotic cell; lipid transport; low-density lipoprotein particle clearance; blood vessel endothelial cell migration; positive regulation of cholesterol storage; phospholipid transport; cholesterol transport; cicatrisation; cholesterol catabolic process; endocytose à récepteur; high-density lipoprotein particle remodeling; positive regulation of endothelial cell migration; androgen biosynthetic process; vitamin transmembrane transport; positive regulation of nitric-oxide synthase activity; endothelial cell proliferation; lipopolysaccharide transport; cholesterol efflux; phagocytosis, recognition; pénétration virale; absorption intestinale; cholesterol homeostasis; regulation of phagocytosis; adhesion of symbiont to host; viral process; detection of lipopolysaccharide; triglyceride homeostasis; reverse cholesterol transport; lipopolysaccharide-mediated signaling pathway; high-density lipoprotein particle clearance;
	Sources:Amigo / QuickGO
Orthologues
	949
	20778
	ENSG00000073060
	ENSMUSG00000037936
	Q8WTV0
	Q61009
	NM_005505; NM_001082959
	NM_001205082; NM_001205083; NM_016741
NP_001076428; NP_005496; NP_001354910; NP_001354911; NP_001354912;
	NP_001354913; NP_001354914; NP_001354915; NP_001354916; NP_001354917; NP_001354918
	NP_001192011; NP_001192012; NP_058021
	Wikidata
Voir/Editer Humain	Voir/Editer Souris

AliasSCARB1

IDs externesOMIM: 601040 MGI: 893578 HomoloGene: 21132 GeneCards: SCARB1

Chr.Chromosome 12 humain^[1]

Fin124,882,668 bp^[1]

Le SCARB1 (pour « Scavenger receptor class B type 1 »), ou SR-BI, est une protéine impliqué dans le métabolisme du cholestérol. Son gène est SCARB1 situé sur le chromosome 12 humain.

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SCARB1

En médecine

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