SLC11A1

SLC11A1
Identifiants
Alias	SLC11A1
IDs externes	OMIM: 600266 MGI: 1345275 HomoloGene: 73884 GeneCards: SLC11A1
Position du gène (humain)
Chr.	Chromosome 2 humain
Fin	218,396,894 bp
Position du gène (souris)
Chr.	Chromosome 1 (souris)
Fin	74,425,221 bp
Expression génique
	Fortement exprimé dans
	poumon droit; ; upper lobe of left lung; ; granulocyte; ; monocyte; ; sang; ; rate; ; buccal mucosa cell; ; left uterine tube; ; left adrenal cortex; ; cellule de la moelle osseuse;
	Fortement exprimé dans
	granulocyte; ; stroma of bone marrow; ; rate; ; artère carotide interne; ; ganglion mésentérique; ; tibiofemoral joint; ; morula; ; corps ciliaire; ; sang; ; corpuscule carotidien;
	Plus de données d'expression de référence
	; ; ; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	manganese ion transmembrane transporter activity; protein homodimerization activity; transition metal ion transmembrane transporter activity; metal ion:proton antiporter activity; metal ion transmembrane transporter activity; cadmium ion transmembrane transporter activity; iron ion transmembrane transporter activity;
Composant cellulaire	integral component of membrane; late endosome; phagocytic vesicle membrane; membrane; late endosome membrane; integral component of plasma membrane; lysosome; endosome membrane; membrane plasmique; tertiary granule membrane; ficolin-1-rich granule membrane;
Processus biologique	manganese ion transmembrane transport; interleukin-3 production; positive regulation of phagocytosis; response to bacterium; response to interferon-gamma; positive regulation of cytokine production; iron ion homeostasis; positive regulation of interferon-gamma production; cicatrisation; ion transport; cellular cadmium ion homeostasis; cell redox homeostasis; T cell proliferation involved in immune response; vacuolar acidification; explosion respiratoire; multicellular organismal iron ion homeostasis; mRNA stabilization; response to lipopolysaccharide; antigen processing and presentation of peptide antigen; positive regulation of dendritic cell antigen processing and presentation; positive regulation of gene expression; iron ion transport; defense response to bacterium; positive regulation of T-helper 1 type immune response; MHC class II biosynthetic process; defense response to Gram-negative bacterium; cadmium ion transmembrane transport; phagocytose; manganese ion transport; nitrite transport; macrophage activation; réponse inflammatoire; T cell cytokine production; interleukin-2 production; negative regulation of cytokine production; activation of protein kinase activity; positive regulation of transcription by RNA polymerase II; cellular iron ion homeostasis; defense response to protozoan; antimicrobial humoral response; neutrophil degranulation; metal ion transport; iron ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologues
	6556
	18173
	ENSG00000018280
	ENSMUSG00000026177
	P49279
	P41251
	NM_000578; NM_001032220
	NM_013612
	NP_000569
	NP_038640
	Wikidata
Voir/Editer Humain	Voir/Editer Souris