SOX9

SOX9
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	4EUW
Identifiants
Alias	SOX9
IDs externes	OMIM: 608160 MGI: 98371 HomoloGene: 294 GeneCards: SOX9
Position du gène (humain)
Chr.	Chromosome 17 humain
Fin	72,126,416 bp
Position du gène (souris)
Chr.	Chromosome 11 (souris)
Fin	112,678,586 bp
Expression génique
	Fortement exprimé dans
	ventricular zone; ; follicule pileux; ; nerf optique; ; parotide; ; épithélium pigmentaire rétinien; ; internal globus pallidus; ; canal galactophore; ; buccal mucosa cell; ; cartilage tissue; ; pylore;
	Fortement exprimé dans
	digit; ; organe cartilagineux; ; os sphénoïde; ; orteil; ; basisphenoid; ; glande lacrymale; ; main bronchus; ; second toe; ; epithelium of seminiferous tubule of testis; ; cervical loop;
	Plus de données d'expression de référence
	; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; core promoter sequence-specific DNA binding; protein kinase activity; protein kinase A catalytic subunit binding; beta-catenin binding; pre-mRNA intronic binding; liaison de chromatine; liaison protéique; liaison ADN; sequence-specific DNA binding; transcription cis-regulatory region binding; bHLH transcription factor binding; cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Composant cellulaire	noyau; transcription regulator complex; nucléoplasme; complexe macromoléculaire;
Processus biologique	skeletal system development; cellular response to retinoic acid; bronchus cartilage development; positive regulation of protein phosphorylation; heart valve development; limb bud formation; positive regulation of protein catabolic process; regulation of transcription by RNA polymerase II; ureter morphogenesis; negative regulation of immune system process; chondrocyte development; positive regulation of cell proliferation involved in heart morphogenesis; oligodendrocyte differentiation; chondrocyte hypertrophy; prostate gland development; lung smooth muscle development; mammary gland development; negative regulation of ossification; negative regulation of photoreceptor cell differentiation; cellular response to mechanical stimulus; intrahepatic bile duct development; regulation of cell adhesion; negative regulation of chondrocyte differentiation; positive regulation of mesenchymal cell proliferation; astrocyte fate commitment; positive regulation of chondrocyte differentiation; spermatogenèse; prostate gland morphogenesis; negative regulation of epithelial cell proliferation; lung epithelial cell differentiation; chondrocyte differentiation involved in endochondral bone morphogenesis; negative regulation of canonical Wnt signaling pathway; endocrine pancreas development; negative regulation of cell population proliferation; regulation of apoptotic process; cellular response to transforming growth factor beta stimulus; negative regulation of mesenchymal cell apoptotic process; Remodelage de la chromatine; negative regulation of myoblast differentiation; positive regulation of branching involved in ureteric bud morphogenesis; cell fate commitment; regulation of transcription, DNA-templated; epidermal growth factor receptor signaling pathway; ostéogenèse; regulation of cell proliferation involved in tissue homeostasis; ureter smooth muscle cell differentiation; ERK1 and ERK2 cascade; notochord development; positive regulation of epithelial cell migration; Sertoli cell differentiation; détermination du sexe masculin; negative regulation of gene expression; transcription, DNA-templated; metanephric nephron tubule formation; régulation positive de la transcription dépendante de l'ADN; développement du cœur; regulation of branching involved in lung morphogenesis; ureter urothelium development; branching involved in ureteric bud morphogenesis; cartilage development; Harderian gland development; positive regulation of kidney development; central nervous system development; heart valve formation; positive regulation of cartilage development; tissue homeostasis; metanephric tubule development; negative regulation of biomineral tissue development; endochondral bone morphogenesis; trachea cartilage development; male germ-line sex determination; lacrimal gland development; voie de signalisation Notch; hair follicle development; différenciation cellulaire; ureter development; regulation of cell cycle process; male gonad development; positive regulation of epithelial cell proliferation; cell fate specification; intestinal epithelial structure maintenance; positive regulation of extracellular matrix assembly; extracellular matrix organization; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; Sertoli cell development; positive regulation of mesenchymal stem cell differentiation; retina development in camera-type eye; cellular response to interleukin-1; Transition épithélio-mésenchymateuse; homeostasis of number of cells within a tissue; negative regulation of transcription, DNA-templated; cAMP-mediated signaling; cartilage condensation; positive regulation of male gonad development; assemblage du nucléosome; negative regulation of bone mineralization; morphogenesis of a branching epithelium; neural crest cell development; protein kinase B signaling; somatic stem cell population maintenance; otic vesicle formation; otic vesicle development; endocardial cushion morphogenesis; cellular response to epidermal growth factor stimulus; positive regulation of epithelial cell differentiation; renal vesicle induction; positive regulation of gene expression; regulation of epithelial cell proliferation involved in lung morphogenesis; regulation of cell population proliferation; heart valve morphogenesis; cytoskeleton organization; cochlea morphogenesis; positive regulation of cell population proliferation; epithelial cell proliferation involved in prostatic bud elongation; retinal rod cell differentiation; protein localization to nucleus; régulation de la différenciation cellulaire; positive regulation of phosphatidylinositol 3-kinase signaling; cellular response to heparin; negative regulation of epithelial cell differentiation; epithelial tube branching involved in lung morphogenesis; transduction de signal; positive regulation of transcription by RNA polymerase II; negative regulation of pri-miRNA transcription by RNA polymerase II; chondrocyte differentiation; neural crest cell fate specification; cellular response to BMP stimulus; cell-cell adhesion; transcription initiation from RNA polymerase II promoter; protein-containing complex assembly; anterior head development; morphogenesis of an epithelium; aortic valve morphogenesis; régulation de l'expression des gènes;
	Sources:Amigo / QuickGO
Orthologues
	6662
	20682
	ENSG00000125398
	ENSMUSG00000000567
	P48436
	Q04887
	NM_000346
	NM_011448
	NP_000337
	NP_035578
	Wikidata
Voir/Editer Humain	Voir/Editer Souris