(R)-limonene 6-monooxygenase
Class of enzymes
From Wikipedia, the free encyclopedia
(R)-limonene 6-monooxygenase (EC 1.14.14.53) is an enzyme that catalyzes the chemical reaction
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| (R)-limonene 6-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.14.53 | ||||||||
| CAS no. | 221461-49-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The four substrates of this enzyme are (+)-(R)-limonene, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are (+)-trans-carveol, oxidised NADP+, and water.[1][2] This enzyme is a cytochrome P450 protein containing heme. This oxidoreductase, which uses molecular oxygen as oxidant, is in a group with systematic name (R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating). Other names in common use include (+)-limonene-6-hydroxylase, and (+)-limonene 6-monooxygenase.[1] It is part of the biosynthesis pathway to (+)-carvone in caraway.[3]
See also
- CYP2C19
- (S)-limonene 6-monooxygenase which converts the opposite enantiomer of limonene to (â)-trans-carveol
