(S)-limonene 6-monooxygenase
Class of enzymes
From Wikipedia, the free encyclopedia
(S)-limonene 6-monooxygenase (EC 1.14.14.51) is an enzyme that catalyzes the chemical reaction
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| (S)-limonene 6-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.14.51 | ||||||||
| CAS no. | 138066-93-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The four substrates of this enzyme are (â)-(S)-limonene, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen and a proton. Its products are (â)-trans-carveol, oxidised NADP+, and water.[1][2]
This enzyme is a cytochrome P450 protein containing heme. This oxidoreductase, which uses molecular oxygen as oxidant is in a group with systematic name (S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating). Other names in common use include (â)-limonene 6-hydroxylase, (â)-limonene 6-monooxygenase, and (â)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating).[1] It is part of the biosynthetic pathway that leads to (â)-carvone, a compound giving spearmint its aroma.[2]
See also
- CYP2C19
- (R)-limonene 6-monooxygenase which converts the opposite enantiomer of limonene to (+)-trans-carveol
