To the play-off qualified the champion of the 1950 Football Championship of the Ukrainian SSR and the worst Ukrainian team of masters of the 1950 Soviet Class B.
Worst team of the Russian SFSR qualified for relegation playoff. Both matches were taken place in Makhachkala. The city of Kalinin were champions of the 1950 Football Championship of the Russian SFSR.
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Dzerzhinets Chelyabinsk |
2–7 |
Kalinin city |
1–0 |
1–7 |
For 1950 MVO Moscow was stationed in city of Kalinin.
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Spartak Ashkhabat |
6–4 |
ODO Ashkhabat |
4–3 |
2–1 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Lokomotiv Petrozavodsk |
4–1 |
ODO Petrozavodsk |
3–1 |
1–0 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Spartak Vilnius |
7–3 |
Inkaras Kaunas |
5–1 |
2–2 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Dinamo Minsk |
0–2 |
ODO Minsk |
0–1 |
0–1 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Dinamo Minsk |
2–1 |
ODO Minsk |
1–1 |
1–0 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Dinamo Alma-Ata |
2–0 |
Dinamo Alma-Ata (reserves) |
1–0 |
1–0 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Burevestnik Kishinev |
10–3 |
Krasnoye Znamia Kishinev |
7–2 |
3–1 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| ODO Tashkent |
4–0 |
Spartak Tashkent |
2–0 |
2–0 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Kalev Tallinn |
10–2 |
Dinamo Tallinn |
3–0 |
7–2 |
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Bolshevik Stalinabad |
w/o |
Dinamo Stalinabad |
|
|
| Team 1 |
Agg.Tooltip Aggregate score |
Team 2 |
1st leg |
2nd leg |
| Trudovye Rezervy Frunze |
w/o |
Spartak Frunze |
|
|