The 1953 season marked the seventh NCAA Baseball Tournament, which consisted of the eight team College World Series. The College World Series was held in Omaha, Nebraska. Districts used a variety of selection methods to the event, from playoffs to a selection committee. District playoffs were not considered part of the NCAA Tournament, and the expansion to eight teams resulted in the end of regionals as they existed from 1947 through 1949. The eight teams played a double-elimination format, with Michigan claiming their first championship with a 7–5 win over Texas in the final.[1]
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| Upper round 1 | | | Upper round 2 | | | Upper final | | | Semifinals | | | Preliminary final | | | Final |
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| Texas | 2 |
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| Duke | 1 | | |
| | | Texas | 7 |
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| | | Lafayette | 2 | | |
| Lafayette | 6 | | | | |
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| Colorado State College | 2 | | |
| | | Texas | 5 |
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| | | Michigan | 12 | |
| Boston College | 4 | | | | | |
| | | | | Michigan | 4 |
| Houston | 1 | | | | |
| | | Boston College | 3 | Texas | 6 | | |
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| | | Michigan | 6 | | | |
| Michigan | 4 | | | | | |
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| Stanford | 0 | | | | Michigan | 7 |
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| | Texas | 13 | | | Texas | 5 |
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| Lower round 1 | Lower round 2 | | | Lafayette | 3 | |
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| | Boston College | 711 |
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| Duke | 3 | | | Duke | 6 |
| | | Boston College | 1 |
| Colorado State College | 2 | | | | | |
| | | Lafayette | 211 | | |
| | Lafayette | 4 | | |
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| Houston | 6 | | | Stanford | 3 |
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| Stanford | 7 | | | |
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