The 1968 season marked the twenty second NCAA baseball tournament, which culminated with the eight team College World Series. The College World Series was held in Omaha, Nebraska. The eight teams played a double-elimination format, with Southern California claiming their fifth championship with a 4–3 win over Southern Illinois in the final.[1]
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| Upper round 1 | | | Upper round 2 | | | Upper final | | | Semifinals | | | Final |
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| Harvard | 0 |
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| St. John's | 2 | | |
| | | St. John's | 312 |
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| | | NC State | 2 | | |
| Southern Illinois | 6 | | | | |
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| NC State | 7 | | |
| | | St. John's | 6 |
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| | | USC | 7 | |
| Texas | 5 | | | | | |
| | | | | USC | 2 |
| Oklahoma State | 8 | | | | |
| | | Oklahoma State | 5 | NC State | 0 | | |
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| | | USC | 6 | | | |
| BYU | 3 | | | | |
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| USC | 5 | | | |
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| | USC | 4 |
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| Lower round 1 | Lower round 2 | | | Southern Illinois | 3 |
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| | Southern Illinois | 7 |
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| Harvard | 1 | | | Oklahoma State | 1 |
| | | Southern Illinois | 15 |
| Southern Illinois | 211 | | | | | |
| | | St. John's | 0 | | |
| | Texas | 5 | | |
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| Texas | 7 | | | NC State | 6 |
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| BYU | 0 | | | |
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