2010 Caribbean Series
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The fifty-second edition of the Caribbean Series (Serie del Caribe) was played in 2010. It was held from February 2 through February 7 with the champions teams from Dominican Republic (Leones del Escogido), Mexico (Naranjeros de Hermosillo), Puerto Rico (Indios de Mayagüez) and Venezuela (Leones del Caracas). The format consisted of 12 games, in a double round-robin format with each team facing each other twice. The games were played at Estadio Nueva Esparta in Porlamar, Margarita Island, Venezuela.
| Country | Club | W | L | W/L % | GB | Managers |
 Dominican Republic | Leones del Escogido | 5 | 1 | .833 | – | Ken Oberkfell |
 Puerto Rico | Indios de Mayagüez | 4 | 2 | .667 | 1 | |
 Mexico | Naranjeros de Hermosillo | 2 | 4 | .333 | 3 | Homar Rojas |
 Venezuela | Leones del Caracas | 1 | 5 | .167 | 4 | Dave Hudgens |
Individual leaders
| Player | Statistic | ||||
| Jesús Feliciano (PUR) | Batting average | .481 | |||
| Kevin Barker (DOM) Fernando Martínez (DOM) | Home runs | 2 | |||
| Juan Francisco (DOM) | RBI | 6 | |||
| Ramón Santiago (DOM) | Runs | 6 | |||
| Jesús Feliciano (PUR) | Hits | 13 | |||
| Juan Francisco (DOM) Armando Ríos (PUR) Chris Roberson (MEX) Ramón Santiago (DOM) Danny Valencia (PUR) | Doubles | 2 | |||
| Miguel Abreu (PUR) Rubén Rivera (MEX) | Triples | 1 | |||
| Freddy Guzmán (DOM) | Stolen bases | 5 | |||
| Kevin Barker (DOM) | OBP | .567 | |||
| Kevin Barker (DOM) | SLG | .800 | |||
| Kevin Barker (DOM) | OPS | 1.657 | |||
| Raúl Valdés (DOM) | Wins | 2 | |||
| Raúl Valdés (DOM) | Strikeouts | 13 | |||
| Pete Parise (PUR) Orlando Román (PUR) | ERA | 0.00 | |||
| Mario Santiago (PUR) | Innings pitched | 12.0 | |||
| Darío Veras (DOM) | Saves | 3 | |||
| Darwin Cubillán (VEN) Gabriel García (VEN) Edgar Huerta (MEX) | Games pitched | 4 | |||