2C-B-3PIP-NBOMe

2C-B-3PIP-NBOMe
Clinical data
Drug class	Serotonin receptor modulator
ATC code	None;
Identifiers
	IUPAC name 3-(4-bromo-2,5-dimethoxyphenyl)-1-[(2-methoxyphenyl)methyl]piperidine;
Chemical and physical data
Formula	C21H26BrNO3
Molar mass	420.347 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1cc(Br)c(cc1C1CCCN(C1)Cc1ccccc1OC)OC;
	InChI InChI=1S/C21H26BrNO3/c1-24-19-9-5-4-7-16(19)14-23-10-6-8-15(13-23)17-11-21(26-3)18(22)12-20(17)25-2/h4-5,7,9,11-12,15H,6,8,10,13-14H2,1-3H3; Key:XCBPFHGQWYIAJG-UHFFFAOYSA-N;

2C-B-3PIP-NBOMe is a serotonin receptor modulator of the phenethylamine, 2C, 3-phenylpiperidine (3PIP), and NBOMe families.^[1]^[2]^[3] It is a cyclized phenethylamine and along with 2C-B-3PIP-POMe is an NBOMe derivative of 2C-B-3PIP.^[1]^[2]^[3] The drug shows very weak affinity for the serotonin 5-HT_2A and 5-HT_2C receptors (K_i = 2,150 nM and 5,880 nM, respectively), with its affinities being profoundly reduced relative to those of 2C-B.^[1]^[2]^[3]^[4] The chemical synthesis of 2C-B-3PIP-NBOMe has been described.^[1]^[2] 2C-B-3PIP-NBOMe was first described in the scientific literature by Martin Hansen in 2010.^[1]^[2]^[3]