2CBecca

Pharmaceutical compound From Wikipedia, the free encyclopedia

2CBecca, also known as 4-(4-bromo-2,5-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline, is a serotonin receptor modulator of the phenethylamine, 2C, and N-benzylphenethylamine families.[1][2] It is a cyclized phenethylamine analogue of the serotonergic psychedelic 25B-NBOMe in which the N-benzylethylamine side chain has been cyclized to form a tetrahydroisoquinoline ring.[1][2] The drug shows affinity for the serotonin 5-HT2A and 5-HT2C receptors (Ki = 39–71 nM and 267–850 nM, respectively).[1][2][3][4] 2CBecca was first described in the scientific literature by Michael Robert Braden of the lab of David E. Nichols at Purdue University in 2007.[2]

ATC code
  • None
FormulaC17H18BrNO2
Molar mass348.240 g·mol−1
Quick facts Clinical data, Drug class ...
2CBecca
Clinical data
Drug classSerotonin receptor modulator
ATC code
  • None
Identifiers
  • 4-(4-bromo-2,5-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline
Chemical and physical data
FormulaC17H18BrNO2
Molar mass348.240 g·mol−1
3D model (JSmol)
  • COc1cc(Br)c(cc1C1CNCc2c1cccc2)OC
  • InChI=1S/C17H18BrNO2/c1-20-16-8-15(18)17(21-2)7-13(16)14-10-19-9-11-5-3-4-6-12(11)14/h3-8,14,19H,9-10H2,1-2H3
  • Key:LRHOKFHXSNZVLA-UHFFFAOYSA-N
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