2CD-2-EtO

2CD-2-EtO, also known as 2-ethoxy-5-methoxy-4-methylphenethylamine, is a psychoactive drug of the phenethylamine, 2C, and TWEETIO families related to the psychedelic drug 2C-D.^[1][2][3] It is the derivative of 2C-D in which the methoxy group at the 2 position has been replaced with an ethoxy group.^[1][2][3]

Other names2CD-2EtO; 2CD-2-ETO; 2CD-2ETO; 2C-D-2-EtO; 2-Ethoxy-5-methoxy-4-methylphenethylamine; 2-Ethoxy-4-methyl-5-methoxyphenethylamine

Routes of
administrationOral^[1][2][3]

Drug classPsychoactive drug

ATC code

• None

Quick facts Clinical data, Other names ...

2CD-2-EtO

Clinical data
Other names	2CD-2EtO; 2CD-2-ETO; 2CD-2ETO; 2C-D-2-EtO; 2-Ethoxy-5-methoxy-4-methylphenethylamine; 2-Ethoxy-4-methyl-5-methoxyphenethylamine
Routes of administration	Oral[1][2][3]
Drug class	Psychoactive drug
ATC code	None
Pharmacokinetic data
Duration of action	~4 hours[1][2][3]
Identifiers
IUPAC name 2-(2-ethoxy-5-methoxy-4-methylphenyl)ethan-1-amine
Chemical and physical data
Formula	C12H19NO2
Molar mass	209.289 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(C(OCC)=C1)=CC(OC)=C1CCN
InChI InChI=1S/C12H19NO2/c1-4-15-12-7-9(2)11(14-3)8-10(12)5-6-13/h7-8H,4-6,13H2,1-3H3 Key:VYXRROQVSSPCGC-UHFFFAOYSA-N

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According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, 2CD-2-EtO's dose is 60 mg orally and its duration is about 4 hours.^[1][2][3] The effects of 2CD-2-EtO have been reported to include feelings of closeness and intimacy between couples without an appreciable state of intoxication.^[1][2][3]

The chemical synthesis of 2CD-2-EtO has been described.^[1]

2CD-2-EtO was first described in the literature by Shulgin in PiHKAL in 1991.^[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.^{[2][4][5][6][7]} The drug is a controlled substance in Canada under phenethylamine blanket-ban language.^[8]