Florence (drug)

Pharmaceutical compound From Wikipedia, the free encyclopedia

Florence, also known as 2-ethoxy-5-methoxy-4-methylamphetamine or as DOM-2ETO, is a chemical compound of the phenethylamine, amphetamine, and DOx families related to DOM.[1][2] It is the derivative of DOM in which the methoxy group at the 2 position has been replaced with an ethoxy group analogously to in the TWEETIO series.[1][2] According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved), Florence may have been synthesized but is not known to have been tested.[1][2] Along with its positional isomer Iris (DOM-5ETO), the compound is one of Shulgin's "ten classic ladies", a series of methylated DOM derivatives.[1][2] Florence was first described in the literature by at least 1970.[1][3] The drug is not an explicitly controlled substance in the United States, but may be considered scheduled as an isomer of DOET.[4][5] It is a controlled substance in Canada due to phenethylamine blanket-ban language.[6]

Other namesFLORENCE; DOM-2ETO; 2-Ethoxy-5-methoxy-4-methylamphetamine; 2-Ethoxy-4-methyl-5-methoxyamphetamine
ATC code
  • None
Quick facts Clinical data, Other names ...
Florence
Clinical data
Other namesFLORENCE; DOM-2ETO; 2-Ethoxy-5-methoxy-4-methylamphetamine; 2-Ethoxy-4-methyl-5-methoxyamphetamine
Routes of
administration
Unknown[1]
ATC code
  • None
Pharmacokinetic data
Duration of actionUnknown[1]
Identifiers
  • 1-(2-ethoxy-5-methoxy-4-methylphenyl)propan-2-amine
Chemical and physical data
FormulaC13H21NO2
Molar mass223.316 g·mol−1
3D model (JSmol)
  • CCOc1cc(C)c(cc1CC(N)C)OC
  • InChI=1S/C13H21NO2/c1-5-16-13-6-9(2)12(15-4)8-11(13)7-10(3)14/h6,8,10H,5,7,14H2,1-4H3
  • Key:JGTKJASRYQAIDY-UHFFFAOYSA-N
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