3,9-dihydroxypterocarpan 6a-monooxygenase
Class of enzymes
From Wikipedia, the free encyclopedia
3,9-dihydroxypterocarpan 6a-monooxygenase (EC 1.14.14.93) is an enzyme that catalyzes the chemical reaction
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| 3,9-dihydroxypterocarpan 6a-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.14.93 | ||||||||
| CAS no. | 92584-16-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The four substrates of this enzyme are (6aR,11aR)-3,9-dihydroxypterocarpan, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are glycinol, oxidised NADP+, and water.[1][2]
3,9-dihydroxypterocarpan 6a-monooxygenase is a cytochrome P450 protein containing heme. It requires a partner, cytochrome P450 reductase which uses NADPH, for functional expression. The systematic name of this enzyme class is (6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating). Other names in common use include 3,9-dihydroxypterocarpan 6a-hydroxylase, and 3,9-dihydroxypterocarpan 6alpha-monooxygenase (erroneous).[1] It is part of the biosynthetic pathway to phytoalexins in soybean.[3]
