3-Fluoroethamphetamine

3-Fluoroethamphetamine (3-FEA) is a stimulant drug of the amphetamine class which acts as a releasing agent of the monoamine neurotransmitters norepinephrine, dopamine and serotonin.

ATC code

• none

Legal status

• CA: Schedule I
• DE: NpSG (Industrial and scientific use only)
• UK: Class A

CAS Number

• 54982-43-3 ^Y

PubChem CID

• 57458869

Quick facts Clinical data, ATC code ...

3-Fluoroethamphetamine

Clinical data
ATC code	none
Legal status
Legal status	CA: Schedule I DE: NpSG (Industrial and scientific use only) UK: Class A
Identifiers
IUPAC name N-ethyl-1-(3-fluorophenyl)propan-2-amine
CAS Number	54982-43-3 Y
PubChem CID	57458869
ChemSpider	27050449 N
UNII	7ZY9F4B6GT
CompTox Dashboard (EPA)	DTXSID201029433
Chemical and physical data
Formula	C11H16FN
Molar mass	181.254 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CC1=CC(F)=CC=C1)NCC
InChI InChI=1S/C11H16FN/c1-3-13-9(2)7-10-5-4-6-11(12)8-10/h4-6,8-9,13H,3,7H2,1-2H3 N Key:CKPWHLGHHXSVJI-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Close

Compared to the unsubstituted ethylamphetamine, 3-fluoroethamphetamine is a weaker releaser of noradrenaline, but a stronger releaser of both dopamine and serotonin, and produced the strongest reinforcing effects in animal studies out of a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser.^[1][2][3][4]