AS-19 (drug)

AS-19 is a substance which acts as a potent agonist at the 5-HT₇ receptor, with an IC₅₀ of 0.83 nM. It reverses the amnesia induced by drugs such as scopolamine and dizocilpine and improves long-term memory acquisition, but inhibits short-term memory formation.^[1][2]

Drug classSerotonin 5-HT₇ receptor agonist

CAS Number

• 1000578-26-6 ^Y

PubChem CID

• 23642275

ChemSpider

• 24605931 ^Y

Quick facts Clinical data, Drug class ...

AS-19

Clinical data
Drug class	Serotonin 5-HT7 receptor agonist
Identifiers
IUPAC name (2S)-N,N-dimethyl-5-(1,3,5-trimethylpyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine
CAS Number	1000578-26-6 Y
PubChem CID	23642275
ChemSpider	24605931 Y
UNII	LA5AQ5R6QS
ChEMBL	ChEMBL2164327
Chemical and physical data
Formula	C18H25N3
Molar mass	283.419 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C(C(=NN1C)C)C2=C3CC[C@@H](CC3=CC=C2)N(C)C
InChI InChI=1S/C18H25N3/c1-12-18(13(2)21(5)19-12)17-8-6-7-14-11-15(20(3)4)9-10-16(14)17/h6-8,15H,9-11H2,1-5H3/t15-/m0/s1 Y Key:BTTOYOKCLDAHHO-HNNXBMFYSA-N Y
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