E-55888

E-55888
Identifiers
	IUPAC name N,N-dimethyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenethylamine;
CAS Number	1034142-33-0;
PubChem CID	24825775;
IUPHAR/BPS	3929;
ChemSpider	34980845;
UNII	4KQ7F7PL4L;
ChEMBL	ChEMBL4205349;
CompTox Dashboard (EPA)	DTXSID901029789 ;
Chemical and physical data
Formula	C16H23N3
Molar mass	257.381 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cn1nc(C)c(c1C)-c(c2)cccc2CCN(C)C;
	InChI InChI=1S/C16H23N3/c1-12-16(13(2)19(5)17-12)15-8-6-7-14(11-15)9-10-18(3)4/h6-8,11H,9-10H2,1-5H3; Key:MFUWRMRKXKCSPL-UHFFFAOYSA-N;
	(verify)

E-55888 is a drug developed by Esteve, which acts as a potent and selective full agonist at the 5HT₇ serotonin receptor, and is used for investigating the role of 5-HT₇ receptors in the perception of pain. When administered by itself, E-55888 is anti-hyperalgesic but not analgesic, but when administered alongside morphine, E-55888 was found to significantly increase the analgesic effects.^[1]^[2]

CAS Number

1034142-33-0

PubChem CID

24825775

IUPHAR/BPS

3929

ChemSpider

34980845

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[2]

E-55888

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Identifiers

IUPAC name N,N-dimethyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenethylamine
CAS Number	1034142-33-0
PubChem CID	24825775
IUPHAR/BPS	3929
ChemSpider	34980845
UNII	4KQ7F7PL4L
ChEMBL	ChEMBL4205349
CompTox Dashboard (EPA)	DTXSID901029789
Chemical and physical data
Formula	C₁₆H₂₃N₃
Molar mass	257.381 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Cn1nc(C)c(c1C)-c(c2)cccc2CCN(C)C
InChI InChI=1S/C16H23N3/c1-12-16(13(2)19(5)17-12)15-8-6-7-14(11-15)9-10-18(3)4/h6-8,11H,9-10H2,1-5H3 Key:MFUWRMRKXKCSPL-UHFFFAOYSA-N
(verify)