Akkermansia glycaniphila
From Wikipedia, the free encyclopedia
| Akkermansia glycaniphila | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Verrucomicrobiota |
| Class: | Verrucomicrobiia |
| Order: | Verrucomicrobiales |
| Family: | Akkermansiaceae |
| Genus: | Akkermansia |
| Species: | A. glycaniphila |
| Binomial name | |
| Akkermansia glycaniphila Ouwerkerk et al. 2016 | |
Akkermansia glycanphila is a species of intestinal mucin-degrading bacterium. It was first isolated from reticulated python (Malayopython reticulatus) feces in 2016.[1]
The genus was named for Antoon DL Akkermans (1940–2006), a Dutch microbiologist recognized for his contribution to microbial ecology, and the epithet from the New Latin and Greek meaning "glycan-loving".[2]
Biology and biochemistry
Akkermansia glycaniphila, like, A. muciniphila is Gram-negative, strictly anaerobic, non-motile, non-spore-forming, oval-shaped bacterium. The typestrain is PytT (=DSM100705T=CIP 110913T). A. glycaniphila is able to use mucin as its sole source of carbon and nitrogen. It is culturable under the same conditions as A. muciniphilia, (anaerobic conditions on medium containing gastric mucin). When grown on soft agar mucin medium, colonies appear white with a diameter of 0.7mm. The long axis of single cells is 0.6–1.0 μm. Cells are covered with filaments, and occur singly, in pairs, in short chains and in aggregates.[1]
The bacterial genome of A. glucaniphila PytT is encoded on a single chromosome of 3,074,121 bp. The G+C content is 57.6% and contains 2,532 coding regions, all 21 tRNA genes, and three complete rRNA operons. For 72% (1,811) of the coding sequences, a function could be predicted. Genome analysis revealed the presence of many mucin-degrading enzymes, of which a number are predicted to be secreted: 54 glycoside hydrolases, one glycosyl hydrolase, seven sialidases, and three sulfatases. The PytT genome is predicted to encode a cytochrome bd ubiquinol oxidase, indicating the potential for aerobic respiration.[3]
The complete genome of A. glycaniphilia has been sequenced.[3]