Alphapapillomavirus
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| Alphapapillomavirus | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Zurhausenvirales |
| Family: | Papillomaviridae |
| Genus: | Alphapapillomavirus |
Alphapapillomavirus is a genus of viruses in the family Papillomaviridae. Humans and monkeys serve as natural hosts. There are 14 species in this genus.[1] Diseases associated with this genus include warts, papillomas, and malignant tumours. The genital-type species known to carry a high risk for malignancy are HPV-16 and 18 (cervical cancer), and those with a low risk of malignancy are HPV-6 and 11 (genital warts).[2][3]
The following species are assigned to the genus:[3]
- Alphapapillomavirus 1
- Alphapapillomavirus 2
- Alphapapillomavirus 3
- Alphapapillomavirus 4
- Alphapapillomavirus 5
- Alphapapillomavirus 6
- Alphapapillomavirus 7
- Alphapapillomavirus 8
- Alphapapillomavirus 9
- Alphapapillomavirus 10
- Alphapapillomavirus 11
- Alphapapillomavirus 12
- Alphapapillomavirus 13
- Alphapapillomavirus 14
Structure
Viruses in Alphapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Alphapapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |