BD1052

BD1052 or N-[2-(3,4-dichlorophenyl)ethyl]-N-2-propen-1-yl-1-pyrrolidineethanamine is a selective sigma receptor agonist, with a reported binding affinity of K_i = 2 ± 0.5 nM for the sigma-1 receptor and 30 times selectivity over the sigma-2 receptor.^[1]

CAS Number

• 138356-16-8

PubChem CID

• 9797436

ChemSpider

• 7973202

UNII

• 9SWF79BC2H

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BD1052

Identifiers
IUPAC name N-[2-(3,4-dichlorophenyl)ethyl]-N-2-propen-1-yl-1-pyrrolidineethanamine
CAS Number	138356-16-8
PubChem CID	9797436
ChemSpider	7973202
UNII	9SWF79BC2H
CompTox Dashboard (EPA)	DTXSID90430892
Chemical and physical data
Formula	C17H24Cl2N2
Molar mass	327.29 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc1ccc(cc1Cl)CCN(CCN2CCCC2)C\C=C
InChI InChI=1S/C17H24Cl2N2/c1-2-8-20(12-13-21-9-3-4-10-21)11-7-15-5-6-16(18)17(19)14-15/h2,5-6,14H,1,3-4,7-13H2 Key:IKFDBDJFYBCATB-UHFFFAOYSA-N

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Consistent with other reported sigma receptor agonists, pretreating Swiss Webster mice with BD1052 significantly increases the behavioral toxicity of cocaine.^[1]