CCNG2
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Cyclin-G2 is a protein that in humans is encoded by the CCNG2 gene.[5][6]
External IDsOMIM: 603203; MGI: 1095734; HomoloGene: 3208; GeneCards: CCNG2; OMA:CCNG2 - orthologs
Function
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.[6]
