CEP68

CEP68
Identifiers
Aliases	CEP68, KIAA0582, centrosomal protein 68
External IDs	OMIM: 616889; MGI: 2667663; HomoloGene: 65235; GeneCards: CEP68; OMA:CEP68 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	65,087,004 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	20,199,429 bp
RNA expression pattern
	Top expressed in
	biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; glutes; ; Skeletal muscle tissue of rectus abdominis; ; skin of hip; ; skin of thigh; ; superficial temporal artery; ; parietal pleura; ; urethra; ; nipple;
	Top expressed in
	Rostral migratory stream; ; digastric muscle; ; extraocular muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; soleus muscle; ; temporal muscle; ; abdominal wall; ; vastus lateralis muscle; ; myocardium of ventricle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein domain specific binding; protein kinase binding; protein binding;
Cellular component	cell junction; nucleus; centrosome; microtubule organizing center; cytoskeleton; cytoplasm; cytosol;
Biological process	protein localization to organelle; centriole-centriole cohesion; centrosome cycle;
	Sources:Amigo / QuickGO
Orthologs
	23177
	216543
	ENSG00000011523
	ENSMUSG00000044066
	Q76N32
	Q8C0D9
	NM_015147; NM_001319100; NM_001319101
	NM_172260
	NP_001306029; NP_001306030; NP_055962
	NP_758464
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein of 68 kDa is a protein that in humans is encoded by the CEP68 gene.^[5]^[6]^[7]^[8] CEP68 is required for centrosome cohesion. It decorates fibres emanating from the proximal ends of centrioles. During mitosis, CEP68 dissociates from centrosomes. CEP68 and rootletin depend on each other for centriole association, and both also require CEP250 for their function.^[9]