CHMP5

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Charged multivesicular body protein 5 is a protein that in humans is encoded by the CHMP5 gene.[4][5][6]

PDBOrtholog search: PDBe RCSB
AliasesCHMP5, C9orf83, HSPC177, PNAS-2, SNF7DC2, Vps60, CGI-34, charged multivesicular body protein 5
Chr.Chromosome 4 (mouse)[1]
Quick facts Available structures, PDB ...
CHMP5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCHMP5, C9orf83, HSPC177, PNAS-2, SNF7DC2, Vps60, CGI-34, charged multivesicular body protein 5
External IDsOMIM: 610900; MGI: 1924209; HomoloGene: 5757; GeneCards: CHMP5; OMA:CHMP5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016410
NM_001195536

NM_029814

RefSeq (protein)

NP_001182465
NP_057494

NP_084090

Location (UCSC)n/aChr 4: 40.95 – 40.97 Mb
PubMed search[2][3]
Wikidata
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Function

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.[6][7]

References

Further reading

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