Cioteronel

Chemical compound From Wikipedia, the free encyclopedia

Cioteronel (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name; developmental code CPC-10997; former tentative brand names Cyoctol, X-Andron) is a nonsteroidal antiandrogen (NSAA) that was never marketed.[1][2][3] It was under development between 1989 and 2001 for the topical treatment of androgenetic alopecia (male pattern baldness), and acne and for the oral treatment of benign prostatic hyperplasia; it reached phase III clinical trials for acne and phase II studies for androgenetic alopecia, but was ultimately discontinued due to poor efficacy.[3][4]

Other namesCPC-10997; Cyoctol; X-Andron
Routes of
administrationBy mouth, topical
Drug classNonsteroidal antiandrogen
ATC code
  • None
Quick facts Clinical data, Other names ...
Cioteronel
Clinical data
Other namesCPC-10997; Cyoctol; X-Andron
Routes of
administration		By mouth, topical
Drug classNonsteroidal antiandrogen
ATC code
  • None
Identifiers
  • 4-(5-methoxyheptyl)-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H28O2
Molar mass252.398 g·mol−1
3D model (JSmol)
  • CCC(CCCCC1CCC2C1CC(=O)C2)OC
  • InChI=InChI=1S/C16H28O2/c1-3-15(18-2)7-5-4-6-12-8-9-13-10-14(17)11-16(12)13/h12-13,15-16H,3-11H2,1-2H3
  • Key:KDULJHFMZBRAHO-UHFFFAOYSA-N
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