DFL23916

DFL23916
Identifiers
	IUPAC name 7-[3-[(4-fluoro-2-methyl-5-phenylphenyl)sulfamoyl]phenyl]heptanoic acid;
PubChem CID	134247381;
Chemical and physical data
Formula	C26H28FNO4S
Molar mass	469.57 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=C(C=C1NS(=O)(=O)C2=CC=CC(=C2)CCCCCCC(=O)O)C3=CC=CC=C3)F;
	InChI InChI=1S/C26H28FNO4S/c1-19-16-24(27)23(21-12-6-4-7-13-21)18-25(19)28-33(31,32)22-14-9-11-20(17-22)10-5-2-3-8-15-26(29)30/h4,6-7,9,11-14,16-18,28H,2-3,5,8,10,15H2,1H3,(H,29,30); Key:VDGLRVBSCZCZGY-UHFFFAOYSA-N;

DFL23916 is an experimental drug which acts as a mixed agonist for the free fatty acid receptors FFAR1 (GPR40) and FFAR4 (GPR120). Unlike the older drug GW9508 which is selective for FFAR1, DFL23916 has a balanced efficacy at both receptor targets. It increases GLP-1 secretion and improved glucose homeostasis in mice.^[1]^[2]

PubChem CID

134247381

FormulaC₂₆H₂₈FNO₄S

Molar mass469.57 g·mol⁻¹

3D model (JSmol)

Interactive image

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[2]

DFL23916

References

Related Articles

Identifiers

IUPAC name 7-[3-[(4-fluoro-2-methyl-5-phenylphenyl)sulfamoyl]phenyl]heptanoic acid
PubChem CID	134247381
Chemical and physical data
Formula	C₂₆H₂₈FNO₄S
Molar mass	469.57 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=CC(=C(C=C1NS(=O)(=O)C2=CC=CC(=C2)CCCCCCC(=O)O)C3=CC=CC=C3)F
InChI InChI=1S/C26H28FNO4S/c1-19-16-24(27)23(21-12-6-4-7-13-21)18-25(19)28-33(31,32)22-14-9-11-20(17-22)10-5-2-3-8-15-26(29)30/h4,6-7,9,11-14,16-18,28H,2-3,5,8,10,15H2,1H3,(H,29,30) Key:VDGLRVBSCZCZGY-UHFFFAOYSA-N