DLST

DLST
Identifiers
Aliases	DLST, DLTS, dihydrolipoamide S-succinyltransferase, PGL7, KGD2
External IDs	OMIM: 126063; MGI: 1926170; HomoloGene: 1456; GeneCards: DLST; OMA:DLST - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	74,903,743 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	85,181,619 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right adrenal cortex; ; left ventricle; ; gastrocnemius muscle; ; left adrenal gland; ; left adrenal cortex; ; right auricle of heart; ; secondary oocyte; ; muscle of thigh; ; skin of leg;
	Top expressed in
	right ventricle; ; muscle of thigh; ; digastric muscle; ; myocardium of ventricle; ; thoracic diaphragm; ; brown adipose tissue; ; right kidney; ; soleus muscle; ; cardiac muscles; ; sternocleidomastoid muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; dihydrolipoyllysine-residue succinyltransferase activity; acyltransferase activity; protein binding;
Cellular component	oxoglutarate dehydrogenase complex; membrane; myelin sheath; mitochondrial matrix; mitochondrion; extracellular exosome; nucleus;
Biological process	tricarboxylic acid cycle; lysine catabolic process; generation of precursor metabolites and energy; L-lysine catabolic process to acetyl-CoA via saccharopine; metabolism; cellular nitrogen compound metabolic process; 2-oxoglutarate metabolic process; succinyl-CoA metabolic process; histone succinylation;
	Sources:Amigo / QuickGO
Orthologs
	1743
	78920
	ENSG00000119689
	ENSMUSG00000004789
	P36957
	Q9D2G2
	NM_001244883; NM_001933
	NM_030225
	NP_001231812; NP_001924
	NP_084501
	Wikidata
View/Edit Human	View/Edit Mouse

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme that in humans is encoded by the DLST gene.^[5]^[6]