DSP-4
Chemical compound
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| Names | |
|---|---|
| Preferred IUPAC name
N-[(2-Bromophenyl)methyl]-2-chloro-N-ethylethan-1-amine | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C11H15BrClN | |
| Molar mass | 276.60 g/mol |
| Density | 1.339 g/cm3 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a monoaminergic neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.[1]
It exerts transient effects in peripheral sympathetic neurons, but more permanent changes within neurons of the central nervous system. It can induce long-term depletion in cortical and spinal levels of noradrenaline.[2]
