Draft:Deutivacaftor

Deutivacaftor
Clinical data
Routes of; administration	By mouth
Identifiers
	IUPAC name N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide;
CAS Number	1413431-07-8 ;
PubChem CID	71470491;
DrugBank	DB15141 ;
ChemSpider	64853784 ;
UNII	SHA6U5FJZL;
KEGG	D11423 ;
ChEBI	CHEBI:66901 ;
ChEMBL	ChEMBL2010601;
Chemical and physical data
Formula	C24H28N2O3
Molar mass	392.499 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [2H]C([2H])([2H])C(c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)(C([2H])([2H])[2H])C([2H])([2H])[2H];
	InChI InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)/i4D3,5D3,6D3 [chembl]; Key:PURKAOJPTOLRMP-ASMGOKTBSA-N [chembl];

Deutivacaftor is a deuterated analogue of the cystic fibrosis drug ivacaftor. It is sold only as part of the combination product vanzacaftor/tezacaftor/deutivacaftor, sold under the brand name Alyftrek. It acts as a CFTR potentiator.^[1]

Draft article not currently submitted for review.

This is a draft Articles for creation (AfC) submission. It is not currently pending review. While there are no deadlines, abandoned drafts may be deleted after six months. To edit or make changes to this draft, simply click on the "Edit" tab at the top of the window.

To be accepted, a draft should:

Show the subject qualifies for a Wikipedia article by using multiple sources that meet four criteria. The sources should be (1) reliable (2) secondary (3) independent of the subject (4) talk about the subject in some depth. For some topics, there are alternative criteria.
Be written from a neutral point of view
Respect copyright and do not plagiarize. Do not copy-paste.

It is strongly discouraged to write about either yourself or your business or employer. If you do so, you must declare it.

Where to get help

If you need help editing or submitting your draft, please ask us a question at the AfC Help Desk or get live help from experienced editors. These venues are only for help with editing and the submission process, not to get reviews.
If you need feedback on your draft, or if the review is taking a lot of time, you can try asking for help on the talk page of a relevant WikiProject. Some WikiProjects are more active than others so a speedy reply is not guaranteed.

How to improve a draft

Wikipedia:Contributing to Wikipedia – a basic overview on how to edit Wikipedia.
Help:Wikitext – how to use the markup
Help:Referencing for beginners – how to include references
Wikipedia:Article development – how to develop your article
Wikipedia:Writing better articles – how to improve your article
Wikipedia:Verifiability – make sure your article includes reliable third-party sources

You can also browse Wikipedia:Featured articles and Wikipedia:Good articles to find examples of Wikipedia's best writing on topics similar to your proposed article.

Improving your odds of a speedy review

To improve your odds of a faster review, tag your draft with relevant WikiProject tags using the button below. This will let reviewers know a new draft has been submitted in their area of interest. For instance, if you wrote about a female astronomer, you would want to add the Biography, Astronomy, and Women scientists tags.

Add tags to your draft

Editor resources

Easy tools: Citation bot (help) | Advanced: Fix bare URLs

Last edited by Boghog (talk | contribs) 32 days ago. (Update)

Submit the draft for review!

Routes of
administrationBy mouth

CAS Number

1413431-07-8^Y

PubChem CID

71470491

DrugBank

DB15141^Y

Quick facts Clinical data, Routes ofadministration ...

Close

[1]

Draft:Deutivacaftor

References

Related Articles

Clinical data

Routes of administration	By mouth
Identifiers
IUPAC name N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
CAS Number	1413431-07-8^Y
PubChem CID	71470491
DrugBank	DB15141^Y
ChemSpider	64853784^Y
UNII	SHA6U5FJZL
KEGG	D11423^N
ChEBI	CHEBI:66901^Y
ChEMBL	ChEMBL2010601
Chemical and physical data
Formula	C₂₄H₂₈N₂O₃
Molar mass	392.499 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES [2H]C([2H])([2H])C(c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)(C([2H])([2H])[2H])C([2H])([2H])[2H]
InChI InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)/i4D3,5D3,6D3^Y[chembl] Key:PURKAOJPTOLRMP-ASMGOKTBSA-N^Y[chembl]