Draft:Edwin Samuel Lennox

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BornEdwin Samuel Lennox

June 9, 1920

Savannah, Georgia, United States
EducationVanderbilt University, NFIP
Known Foranti-A mAb reagent, "Lennox" lysogeny broth
FieldsPhysics, microbiology, cellular and molecular immunology, biology, biochemistry, chemistry
Quick facts Born, Education ...
Edwin S. Lennox
BornEdwin Samuel Lennox

June 9, 1920

Savannah, Georgia, United States
EducationVanderbilt University, NFIP
Known Foranti-A mAb reagent, "Lennox" lysogeny broth
FieldsPhysics, microbiology, cellular and molecular immunology, biology, biochemistry, chemistry
InstitutionsUniversity of Michigan, University of Illinois, Cambridge University, New York University
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Introduction

Edwin Samuel Lennox was a cellular and molecular immunologist and an expert physicist. Lennox was born on June 9th, 1920 in Savannah, Georgia. He was born into a family of 5. He had two brothers growing up, Bernie Lennox and John Lennox.[1]. He left Savannah to attend college at the University of Vanderbilt to complete his undergraduate degree and then went on to attend the University of Rochester for graduate school. During his graduate years, he received a letter from a Victor Weisskopf inviting him to work on a project in New Mexico, this project is now known as the Manhattan Project [2][3].

He ended up pivoting away from physics when he took a seminar that was taught by Melvin Cohn at Cold Spring Harbor Laboratory. Edwin became very interested in this work and decided to join Cohn's lab to continue this work in cellular and molecular immunology. Later in 1961, Lennox worked at Pasteur Institute in Paris, France alongside Melvin Cohn. While he was working at this Institute he was asked by Jonas Salk to come work at the Salk Institute. He was one of the first four fellows that were asked to work at the Salk Institute [4].

Lennox married Helen Carey Lennox, to whom he was married to for 46 years. During their time together they had five children, Dan Smith, Nena Thomas, Caroline Lennox, and Carla Lennox.

Works and Achievements

Government issued ID badge belonging to young Edwin Lennox authorizing him to work on the Manhattan Project.

After studying at Vanderbilt University under Max Delbruck, Lennox received an undergraduate degree [4]. Lennox was recruited by a professor of his at Rochester, Victor Weisskopf, to help with the Manhattan Project alongside Feynman and Szilard in Los Alamos, New Mexico [4][5][3]. In 1944, Edwin was assigned as a civilian to work with Wiesskopf, under Hans Bethe, in the Theoretical Physics Division. The following summer, Lennox traveled to a site near Alamogordo to set up equipment for the testing of the atomic bomb. After watching the first explosion, the Trinity test, Lennox said, "It was one of those life-changing experiences [3]."

At the close of the war, Lennox earned his PhD in theoretical physics as a student under his prior mentor, Hans Bethe. Edwin then worked as an assistant physics professor at the University of Michigan, with a summer job teaching physics at the University of Illinois. He shifted his studies to biology, performing phage experiments. Lennox was sponsored for a post-doctoral fellowship from the National Foundation for Infantile Paralysis (NFIP).He worked on photo-reactivation of UV-inactivated phages and transduction [3].

Lennox then further specified his work into immunology. Lennox joined Melvin Cohn's lab and dove into the field of cellular and molecular immunology. His fellowship with the NFIP ended in 1956, and he took up work as a biochemistry instructor, while simultaneously studying biochemistry, genetics, and chemistry. He worked up the ladder to become an associate professor of biochemistry, while still working with Cohn. In 1960, Lennox again relocated to teach microbiology at NYU [3].

While working with Cohn and Jacques Monod, Lennox was invited to join the Salk institute. Cohn was also invited, with both scientists being given an 8,000 square foot lab in the North Building [4][6].

In 1974, Lennox began work at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) at Cambridge. In 1978, Lennox and his student, Steven Sacks, found upon their second attempt, a successful anti-A mAb reagent used in blood typing [7]. This launched a partnership between biotechnology Celltech and MRC [8]. In 1983, Lennox was hired as a project manager for Celltech, and soon became the director of research [9].

Selected Publications

  • Dennert G, Lennox ES. Phagocytic cells as effectors in a cell-mediated immunity system. J Immunol. 1973 Dec;111(6):1844-54. PMID: 4543031.
  • Dennert G, Lennox ES. Cooperation and cell-mediated cytotoxicity as functions of two subsets of T cells. J Immunol. 1974 Nov;113(5):1553-61. PMID: 4213868.
  • Tucker DF, Dennert G, Lennox ES. Thymus-derived lymphocytes as effectors of cell-mediated immunity to syngeneic and allogeneic transplants in the rat. J Immunol. 1974 Oct;113(4):1302-12. PMID: 4547337.
  • Dennert G, Lennox E. Cell interactions in humoral and cell-mediated immunity. Nat New Biol. 1972 Jul 26;238(82):114-6. doi: 10.1038/newbio238114a0. PMID: 4558265.
  • Dennert G, Lennox ES. Lymphoid cell interactions in cell-mediated immunity. Adv Exp Med Biol. 1973;29(0):157-66. doi: 10.1007/978-1-4615-9017-0_23. PMID: 4546858.
  • Dennert G, Lennox ES. Rat thoracic duct cells as a substitute for T cells and carrier in the antibody response of mouse spleens deficient in thymus cells. Nat New Biol. 1973 Jun 13;243(128):214-6. doi: 10.1038/newbio243214a0. PMID: 4541396.
  • Trowbridge IS, Lennox ES, Porter RR. Induction in vitro of hapten specific plaque forming cells. Nature. 1970 Dec 12;228(5276):1087-9. doi: 10.1038/2281087a0. PMID: 4921665.
  • Kennedy JC, Treadwell PE, Lennox ES. Antigen-specific synergism in the immune response of irradiated mice given marrow cells and peritoneal cavity cells or extracts. J Exp Med. 1970 Aug 1;132(2):353-67. doi: 10.1084/jem.132.2.353. PMID: 4927598; PMCID: PMC2138736.
  • Takei F, Waldmann H, Lennox ES, Milstein C. Monoclonal antibody H9/25 reacts with functional subsets of T and B cells: killer, killer precursor and plaque-forming cells. Eur J Immunol. 1980 Jul;10(7):503-9. doi: 10.1002/eji.1830100704. PMID: 6447609.
  • Takei F, Galfrè G, Alderson T, Lennox ES, Milstein C. H 9/25 monoclonal antibody recognizes a new allospecificity of mouse lymphocyte subpopulations: strain and tissue distribution. Eur J Immunol. 1980 Apr;10(4):241-6. doi: 10.1002/eji.1830100404. PMID: 7398756.
  • Milstein C, Lennox E. The use of monoclonal antibody techniques in the study of development cell surfaces. Curr Top Dev Biol. 1980;14(Pt 2):1-32. doi: 10.1016/s0070-2153(08)60187-8. PMID: 7006924.
  • Voak D, Sacks S, Alderson T, Takei F, Lennox E, Jarvis J, Milstein C, Darnborough J. Monoclonal anti-A from a hybrid-myeloma: evaluating as a blood grouping reagent. Vox Sang. 1980 Sep;39(3):134-40. doi: 10.1111/j.1423-0410.1980.tb01848.x. PMID: 7210604.
  • Stern PL, Willison KR, Lennox E, Galfrè G, Milstein C, Secher D, Ziegler A. Monoclonal antibodies as probes for differentiation and tumor-associated antigens: a Forssman specificity on teratocarcinoma stem cells. Cell. 1978 Aug;14(4):775-83. doi: 10.1016/0092-8674(78)90333-1. PMID: 567532.
  • Smedley HM, Finan P, Lennox ES, Ritson A, Takei F, Wraight P, Sikora K. Localisation of metastatic carcinoma by a radiolabelled monoclonal antibody. Br J Cancer. 1983 Feb;47(2):253-9. doi: 10.1038/bjc.1983.33. PMID: 6337613; PMCID: PMC2011266.
  • Finan PJ, Grant RM, de Mattos C, Takei F, Berry PJ, Lennox ES, Bleehen NM. Immunohistochemical techniques in the early screening of monoclonal antibodies to human colonic epithelium. Br J Cancer. 1982 Jul;46(1):9-17. doi: 10.1038/bjc.1982.158. PMID: 7049214; PMCID: PMC2011068.
  • Voak D, Lennox E, Sacks S, Milstein C, Darnborough J. Monoclonal anti-A and anti-B: development as cost-effective reagents. Med Lab Sci. 1982 Apr;39(2):109-22. PMID: 6811828.
  • Evan GI, Lennox ES, Alderson T, Croft L. A monoclonal anti-HLA antibody recognizes a mouse tumor-associated antigen. Eur J Immunol. 1983 Feb;13(2):160-6. doi: 10.1002/eji.1830130213. PMID: 6601010.
  • Lennox ES. Genetic control of the antibody response. Biochem J. 1970 Apr;117(2):2P. doi: 10.1042/bj1170002pa. PMID: 5420038; PMCID: PMC1178880.
  • Lennox ES. The genetics of the immune response. Proc R Soc Lond B Biol Sci. 1966 Nov 22;166(1003):222-31. doi: 10.1098/rspb.1966.0095. PMID: 4382712.
  • Sacks SH, Lennox ES. Monoclonal anti-B as a new blood-typing reagent. Vox Sang. 1981 Feb;40(2):99-104. doi: 10.1111/j.1423-0410.1981.tb00677.x. PMID: 6785927.
  • Lowe AD, Green SM, Voak D, Gibson T, Lennox ES. A human-human monoclonal anti-D by direct fusion with a lymphoblastoid line. Vox Sang. 1986;51(3):212-6. doi: 10.1111/j.1423-0410.1986.tb01955.x. PMID: 3101287.
  • Lowe AD, Lennox ES, Voak D. A new monoclonal anti-A. Culture supernatants with the performance of hyperimmune human reagents. Vox Sang. 1984;46(1):29-35. doi: 10.1111/j.1423-0410.1984.tb00044.x. PMID: 6422633.
  • Nordhagen R, Sundvall K, Sacks S, Lennox E. Monoclonal anti-A and anti-B on Groupamatic. Vox Sang. 1983;44(2):90-1. doi: 10.1111/j.1423-0410.1983.tb04107.x. PMID: 6829186.
  • Gooi HC, Hounsell EF, Picard JK, Lowe AD, Voak D, Lennox ES, Feizi T. Differing reactions of monoclonal anti-A antibodies with oligosaccharides related to blood group A. J Biol Chem. 1985 Oct 25;260(24):13218-24. PMID: 2414277.
  • Finan PJ, Wight DG, Lennox ES, Sacks SH, Bleehen NM. Human blood group isoantigen expression on normal and malignant gastric epithelium studied with anti-A and anti-B monoclonal antibodies. J Natl Cancer Inst. 1983 Apr;70(4):679-85. PMID: 6572756.
  • Deans JA, Alderson T, Thomas AW, Mitchell GH, Lennox ES, Cohen S. Rat monoclonal antibodies which inhibit the in vitro multiplication of Plasmodium knowlesi. Clin Exp Immunol. 1982 Aug;49(2):297-309. PMID: 6751636; PMCID: PMC1536485.
  • Sikora K, Stern P, Lennox E. Immunoprotection by embryonal carcinoma cells for methylcholanthrene-induced murine sarcomas. Nature. 1977 Oct 27;269(5631):813-5. doi: 10.1038/269813a0. PMID: 927507.
  • Pearson T, Sikora K, Lennox E. Measurement of H-2 antigen and immunogenicity of methylcholanthrene-induced murine sarcomas. Br J Cancer. 1978 Apr;37(4):530-5. doi: 10.1038/bjc.1978.81. PMID: 77161; PMCID: PMC2009572.
  • Sikora K, Koch G, Brenner S, Lennox E. Partial purification of tumour-specific transplantation antigens from methylcholanthrene-induced murine sarcomas by immobilized lectins. Br J Cancer. 1979 Dec;40(6):831-8. doi: 10.1038/bjc.1979.273. PMID: 93484; PMCID: PMC2010135.
  • Finan PJ, Anderson JR, Doyle PT, Lennox ES, Bleehen NM. The prediction of invasive potential in superficial transitional cell carcinoma of the bladder. Br J Urol. 1982 Dec;54(6):720-5. doi: 10.1111/j.1464-410x.1982.tb13633.x. PMID: 6758916.
  • Lennox ES, Sikora K. Tumor-specific transplantation antigens of chemically induced tumors. Adv Pathobiol. 1977;(6):68-78. PMID: 70987.
  • Sikora K, Alderson T, Finan P, Lennox E, Markham N, Ritson A, Smedley H. The selection of monoclonal antibodies for tumour localization in patients with colorectal carcinoma. Med Oncol Tumor Pharmacother. 1984;1(2):63-71. doi: 10.1007/BF02934976. PMID: 6544894.
  • Vowden P, Lowe AD, Lennox ES, Bleehen NM. Thyroid blood group isoantigen expression: a parallel with ABH isoantigen expression in the distal colon. Br J Cancer. 1986 Jun;53(6):721-5. doi: 10.1038/bjc.1986.124. PMID: 3521695; PMCID: PMC2001419.
  • Evan GI, Lennox ES, Lowe AD, Cohn JD. Tumour specific transplantation antigens of chemically induced rodent tumours. Prog Clin Biol Res. 1983;132B:355-61. PMID: 6195668.
  • Evan GI, Lennox ES. Retroviral antigens and tumours. Br Med Bull. 1985 Jan;41(1):59-62. doi: 10.1093/oxfordjournals.bmb.a072026. PMID: 2982448.
  • Lennox ES, Lowe AD, Cohn J, Evan G. Specific antigens on methylcholanthrene-induced tumors of mice. Transplant Proc. 1981 Dec;13(4):1759-61. PMID: 6173943.
  • Vowden P, Lowe AD, Lennox ES, Bleehen NM. The expression of ABH and Y blood group antigens in benign and malignant breast tissue: the preservation of the H and Y antigens in malignant epithelium. Br J Cancer. 1986 Mar;53(3):313-9. doi: 10.1038/bjc.1986.54. PMID: 3516191; PMCID: PMC2001362.
  • Vowden P, Lowe AD, Lennox ES, Bleehen NM. Are blood group isoantigens lost from malignant prostatic epithelium? Immunohistochemical support for the preservation of the H isoantigen. Br J Cancer. 1986 Mar;53(3):307-12. doi: 10.1038/bjc.1986.53. PMID: 2421753; PMCID: PMC2001367.
  • DRAY S, DUBISKI S, KELUS A, LENNOX ES, OUDIN J. A notation for allotypy. Nature. 1962 Aug 25;195:785-6. doi: 10.1038/195785a0. PMID: 13887753.
  • Zamoyska R, Waldman H, Prospero T, Lennox E. Identification of phenotypically distinct subpopulations of cytotoxic T lymphocytes. Mol Biol Med. 1983 Jul;1(1):137-50. PMID: 6333573.
  • Watt SM, Sala-Newby G, Hoang T, Gilmore DJ, Grunert F, Nagel G, Murdoch SJ, Tchilian E, Lennox ES, Waldmann H. CD66 identifies a neutrophil-specific epitope within the hematopoietic system that is expressed by members of the carcinoembryonic antigen family of adhesion molecules. Blood. 1991 Jul 1;78(1):63-74. PMID: 1712645.
  • Soos MA, Siddle K, Baron MD, Heward JM, Luzio JP, Bellatin J, Lennox ES. Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor. Biochem J. 1986 Apr 1;235(1):199-208. doi: 10.1042/bj2350199. PMID: 2427071; PMCID: PMC1146668.
  • Redmond S, Brady D, Clements I, Holmes-Ievers E, Hill C, Kipp D, Lawson AD, Lennox ES, Lloyd JC, Price-Jones E, et al. Monoclonal antibodies for purification and assay of IL-2. Lymphokine Res. 1986;5 Suppl 1:S29-34. PMID: 3491261.
  • Ciclitira PJ, Ellis HJ, Evans DJ, Lennox ES. A radioimmunoassay for wheat gliadin to assess the suitability of gluten free foods for patients with coeliac disease. Clin Exp Immunol. 1985 Mar;59(3):703-8. PMID: 3987095; PMCID: PMC1576931.
  • Ciclitira PJ, Ellis HJ, Evans DJ, Lennox ES. Relation of antigenic structure of cereal proteins to their toxicity in coeliac patients. Br J Nutr. 1985 Jan;53(1):39-45. doi: 10.1079/bjn19850008. PMID: 2415155.
  • Pauza CD, Bleil JD, Lennox ES. The control of transferrin receptor synthesis in mitogen-stimulated human lymphocytes. Exp Cell Res. 1984 Oct;154(2):510-20. doi: 10.1016/0014-4827(84)90175-7. PMID: 6090187.
  • Ciclitira PJ, Evans DJ, Fagg NL, Lennox ES, Dowling RH. Clinical testing of gliadin fractions in coeliac patients. Clin Sci (Lond). 1984 Mar;66(3):357-64. doi: 10.1042/cs0660357. PMID: 6692666.
  • Ciclitira PJ, Lennox ES. A radioimmunoassay for alpha- and beta-gliadins. Clin Sci (Lond). 1983 Jun;64(6):655-9. doi: 10.1042/cs0640655. PMID: 6839670.
  • Lennox ES. How are tumour antigens related to normal antigens? Ciba Found Symp. 1983;96:89-103. doi: 10.1002/9780470720776.ch6. PMID: 6343008.
  • Ciclitira PJ, Hunter JO, Lennox ES. Clinical testing of bread made from nullisomic 6A wheats in coeliac patients. Lancet. 1980 Aug 2;2(8188):234-6. doi: 10.1016/s0140-6736(80)90123-3. PMID: 6105397.
  • Cioli D, Lennox ES. Purification and characterization of nascent chains from immunoglobulin producing cells. Biochemistry. 1973 Aug 14;12(17):3203-10. doi: 10.1021/bi00741a010. PMID: 4732858.
  • Cioli D, Lennox ES. Immunoglobulin nascent chains on membrane-bound ribosomes of myeloma cells. Biochemistry. 1973 Aug 14;12(17):3211-7. doi: 10.1021/bi00741a011. PMID: 4581785.
  • Knopf PM, Munro AJ, Lennox ES. Synthesis of an immunoglobulin light chain: pulse-labeling studies. Arch Biochem Biophys. 1973 Jul;157(1):285-302. doi: 10.1016/0003-9861(73)90414-1. PMID: 4716957.
  • Lindstrom JM, Singer SJ, Lennox ES. The effects of reducing and alkylating agents on the acetylcholine receptor activity of frog sartorius muscle. J Membr Biol. 1973 Feb 27;11(3):217-26. doi: 10.1007/BF01869823. PMID: 4706262.
  • Lindstrom JM, Singer SJ, Lennox ES. Study of frog sartorius muscle acetylcholine receptor using the irreversible inhibitor TDF. J Membr Biol. 1972 Dec;9(1):155-76. doi: 10.1007/BF01868050. PMID: 24177646.
  • Hirano H, Parkhouse B, Nicolson GL, Lennox ES, Singer SJ. Distribution of saccharide residues on membrane fragments from a myeloma-cell homogenate: its implications for membrane biogenesis. Proc Natl Acad Sci U S A. 1972 Oct;69(10):2945-9. doi: 10.1073/pnas.69.10.2945. PMID: 4117011; PMCID: PMC389680.
  • Lindstrom JM, Singer SJ, Lennox ES. Study of frog sartorius muscle acetylcholine receptor using the irreversible inhibitor TDF. J Membr Biol. 1972;9(2):155-76. PMID: 5084458.
  • Choi YS, Knopf PM, Lennox ES. Intracellular transport and secretion of an immunoglobulin light chain. Biochemistry. 1971 Feb 16;10(4):668-79. doi: 10.1021/bi00780a019. PMID: 5544658.
  • Choi YS, Knopf PM, Lennox ES. Subcellular fractionation of mouse myeloma cells. Biochemistry. 1971 Feb 16;10(4):659-67. doi: 10.1021/bi00780a018. PMID: 5544657.
  • Kiefer H, Lindstrom J, Lennox ES, Singer SJ. Photo-affinity labeling of specific acetylcholine-binding sites on membranes. Proc Natl Acad Sci U S A. 1970 Dec;67(4):1688-94. doi: 10.1073/pnas.67.4.1688. PMID: 5275370; PMCID: PMC283413.
  • Knopf PM, Parkhouse RM, Lennox ES. Biosynthetic units of an immunoglobulin heavy chain. Proc Natl Acad Sci U S A. 1967 Dec;58(6):2288-95. doi: 10.1073/pnas.58.6.2288. PMID: 4173584; PMCID: PMC223833.
  • Lennox ES, Cohn M. Immunoglobulins. Annu Rev Biochem. 1967;36:365-406. doi: 10.1146/annurev.bi.36.070167.002053. PMID: 18257726.
  • Stemke GW, Lennox ES. Bacteriophage neutralizing activity of fragments derived from rabbit immunoglobulin by papain digestion. J Immunol. 1967 Jan;98(1):94-101. PMID: 4163641.
  • Melchers F, Lennox ES, Facon M. A carbohydrate-containing mouse light chain-protein. Biochem Biophys Res Commun. 1966 Jul 20;24(2):244-51. doi: 10.1016/0006-291x(66)90727-3. PMID: 5965233.
  • Potter DD, Furshpan EJ, Lennox ES. Connections between cells of the developing squid as revealed by electrophysiological methods. Proc Natl Acad Sci U S A. 1966 Feb;55(2):328-36. doi: 10.1073/pnas.55.2.328. PMID: 5220950; PMCID: PMC224144.
  • ATTARDI G, COHN M, HORIBITA K, LENNOX ES. ANTIBODY FORMATION BY RABBIT LYMPH NODE CELLS. V. CELLULAR HETEROGENEITY IN THE PRODUCTION OF ANTIBODY TO T5. J Immunol. 1964 Jul;93:94-5. PMID: 14214396.
  • ATTARDI G, COHN M, HORIBATA K, LENNOX ES. ANTIBODY FORMATION BY RABBIT LYMPH NODE CELLS. IV. THE DETAILED METHODS FOR MEASURING ANTIBODY SYNTHESIS BY INDIVIDUAL CELLS, THE KINETICS OF ANTIBODY FORMATION BY RABBITS AND THE PROPERTIES OF CELL SUSPENSIONS. J Immunol. 1964 Mar;92:372-90. PMID: 14131461.
  • ATTARDI G, COHN M, HORIBATA K, LENNOX ES. ANTIBODY FORMATION BY RABBIT LYMPH NODE CELLS.III. THE CONTROLS FOR MICRODROP AND MICROPIPET EXPERIMENTS. J Immunol. 1964 Mar;92:356-71. PMID: 14128984.
  • ATTARDI G, COHN M, HORIBATA K, LENNOX ES. ANTIBODY FORMATION BY RABBIT LYMPH NODE CELLS. II. FURTHER OBSERVATIONS ON THE BEHAVIOR OF SINGLE ANTIBODY-PRODUCING CELLS WITH RESPECT TO THEIR SYNTHETIC CAPACITY AND MORPHOLOGY. J Immunol. 1964 Mar;92:346-55. PMID: 14128983.
  • ATTARDI G, COHN M, HORIBATA K, LENNOX ES. ANTIBODY FORMATION BY RABBIT LYMPH NODE CELLS. I. SINGLE CELL RESPONSES TO SEVERAL ANTIGENS. J Immunol. 1964 Mar;92:335-45. PMID: 14128982.
  • ATTARDI G, COHN M, HORIBATA K, LENNOX ES. Symposium on the biology of cells modified by viruses or antigens. II. On the analysis of antibody synthesis at the cellular level. Bacteriol Rev. 1959 Dec;23(4):213-23. doi: 10.1128/br.23.4.213-223.1959. PMID: 13794995; PMCID: PMC181035.
  • YANOFSKY C, LENNOX ES. Transduction and recombination study of linkage relationships among the genes controlling tryptophan synthesis in Escherichia coli. Virology. 1959 Aug;8:425-47. doi: 10.1016/0042-6822(59)90046-7. PMID: 13846453.
  • LENNOX ES, KAPLAN AS. Action of diphtheria toxin on cells cultivated in vitro. Proc Soc Exp Biol Med. 1957 Aug-Sep;95(4):700-2. doi: 10.3181/00379727-95-23335. PMID: 13465775.
  • LENNOX ES. Transduction of linked genetic characters of the host by bacteriophage P1. Virology. 1955 Jul;1(2):190-206. doi: 10.1016/0042-6822(55)90016-7. PMID: 13267987.
  • LENNOX ES, LURIA SE, BENZER S. On the mechanism of photoreactivation of ultraviolet-inactivated bacteriophage. Biochim Biophys Acta. 1954 Dec;15(4):471-4. doi: 10.1016/0006-3002(54)90003-7. PMID: 13230093.

Teaching Experience

After Lennox finished his Ph.D. in theoretical physics in 1948, he moved to Ann Arbor to become an assistant professor at the University of Michigan. At this point, his focus shifted from physics to immunology and research became a priority [3]. In 1960, he went on to work with Melvin Cohn at Washington University as an associate professor of microbiology. The two worked with antibodies and the human immune system. In 1961, he moved on teach at the Pasteur Institute in France. During his time there, he continued to research and teach cellular and molecular immunology. In 1962, Lennox resigned from the Pasteur Institute and joined the Salk Institute[3][4].

At the Salk Institute, Lennox and Cohn received a grant to fund an Antibody Workshop. The workshop in 1965 was focused on protein sequencing. These workshops accelerated progress in the field of molecular biology. Lennox took a leave of absence and worked in England in the early 1970s[3].

While at the Salk Institute, Lennox and Cohn recognized the growing interest and confusion in antibodies so he obtained a grant to support a workshop. These workshops were small functions aimed at those new to the field. The lively discussions resulted in experiment proposals, criticisms, and ideas which accelerated progress in the field of molecular biology[3]. Lennox would take some time to various classes at the World Health organization[4]. Lennox had many promising students who were interested in his line of work, they worked with him in his laboratory at the Salk Institute [5].

Death Edwin Lennox passed away on August 21st, 2018, at the age of 98. He was buried in the place he grew up and called home, Savannah, Georgia.

References

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